SubtiBank SubtiBank

Categories containing this gene/protein


transcription factors and their control, resistance against toxic metals, Skin element

This gene is a member of the following regulons


ArsR regulon, SigF regulon

The ArsR regulon


Gene


  • Coordinates on the chromosome (coding sequence): 2,657,317 -> 2,657,634
  • The protein


    Catalyzed reaction/ biological activity

    Protein family

  • ArsR family
  • Paralogous protein(s)

    Kinetic information

    Domains

    Modification

    Cofactors

    Effectors of protein activity

    Structure

    Localization

    Interactions

    Additional information

    Expression and Regulation


    Operon

  • arsR-yqcK-arsB-arsC PubMed
  • Sigma factor

  • SigA PubMed, SigF PubMed
  • Regulation

  • expressed early during sporulation in the forespore (SigF) PubMed
  • expressed in the presence of toxic metal ions (As(III), Cd(II) and Ag(I)) (ArsR) PubMed
  • Regulatory mechanism

  • ArsR: transcription repression PubMed
  • Additional information

    Biological materials


    Mutant

    Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct

    Antibody

    Labs working on this gene/protein


    References


    Wang ST, Setlow B, Conlon EM, Lyon JL, Imamura D, Sato T, Setlow P, Losick R, Eichenberger P

    The forespore line of gene expression in Bacillus subtilis

    J Mol Biol. 2006 Apr 21;358(1):16-37. Epub 2006 Feb 8. PubMed PMID: 16497325.
    Moore CM, Gaballa A, Hui M, Ye RW, Helmann JD

    Genetic and physiological responses of Bacillus subtilis to metal ion stress

    Mol Microbiol. 2005 Jul;57(1):27-40. PubMed PMID: 15948947.
    Sato T, Kobayashi Y

    The ars operon in the skin element of Bacillus subtilis confers resistance to arsenate and arsenite

    J Bacteriol. 1998 Apr;180(7):1655-61. PubMed PMID: 9537360; PubMed Central PMCID: PMC107075.
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