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Categories containing this gene/protein


Other regulators

This gene is a member of the following regulons


AbrB regulon

The BmrB regulon


Gene


  • Coordinates on the chromosome (coding sequence): 1,045,037 -> 1,045,198
  • The protein


    Catalyzed reaction/ biological activity

    Protein family

    Paralogous protein(s)

    Kinetic information

    Domains

    Modification

    Cofactors

    Effectors of protein activity

    Structure

    Localization

    Interactions

    Additional information

    Expression and Regulation


    Operon

  • bmrB-bmrC-bmrD PubMed
  • Sigma factor

    Regulation

  • bmrB-bmrC-bmrD expression only occurs during the late-exponential and stationary growth stages (AbrB) PubMed
  • Regulatory mechanism

  • AbrB: transcription repression PubMed
  • Additional information

    Biological materials


    Mutant

  • MGNA-A706 (yheJ::erm), available at the NBRP B. subtilis, Japan
  • Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct

    Antibody

    Labs working on this gene/protein


    References


    Reilman E, Mars RA, van Dijl JM, Denham EL

    The multidrug ABC transporter BmrC/BmrD of Bacillus subtilis is regulated via a ribosome-mediated transcriptional attenuation mechanism

    Nucleic Acids Res. 2014 Oct;42(18):11393-407. doi: 10.1093/nar/gku832. Epub 2014 Sep 12. PubMed PMID: 25217586; PubMed Central PMCID: PMC4191407.
    Chumsakul O, Takahashi H, Oshima T, Hishimoto T, Kanaya S, Ogasawara N, Ishikawa S

    Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation

    Nucleic Acids Res. 2011 Jan;39(2):414-28. doi: 10.1093/nar/gkq780. Epub 2010 Sep 3. PubMed PMID: 20817675; PubMed Central PMCID: PMC3025583.
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