SubtiBank SubtiBank
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Categories containing this gene/protein


transcription factors and their control, resistance against oxidative and electrophile stress

This gene is a member of the following regulons


The CatR regulon


Gene


  • Coordinates on the chromosome (coding sequence): 3,457,615 -> 3,457,941
  • Phenotypes of a mutant

  • increased resistance to catechol and quinones PubMed
  • The protein


    Catalyzed reaction/ biological activity

  • [[MarR/DUF24 family]] transcription repressor of the catD-catE operon PubMed
  • Protein family

  • [[MarR/DUF24 family]]
  • Paralogous protein(s)

  • YodB
  • Kinetic information

    Domains

    Modification

  • in responsse to the presence of diamides or quinones, Cys-7 forms intermolecular disulfide bonds, this results in loss of DNA-bindig ability (induction of catD-catE) PubMed
  • Cofactors

    Effectors of protein activity

    Structure

    Localization

    Interactions

    Additional information

    Expression and Regulation


    Operon

    Sigma factor

    Regulation

    Regulatory mechanism

    Additional information

    Biological materials


    Mutant

  • MGNA-A451 (yvaP::erm), available at the NBRP B. subtilis, Japan
  • Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct

    Antibody

    Labs working on this gene/protein


  • Haike Antelmann,University of Greifswald, Germany
  • References


    Antelmann H(1), Hecker M, Zuber P.

    Proteomic signatures uncover thiol-specific electrophile resistance mechanisms in Bacillus subtilis.

    Expert Rev Proteomics. 2008 Feb;5(1):77-90. doi: 10.1586/14789450.5.1.77.
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