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Categories containing this gene/protein


sulfur metabolism, transcription factors and their control

This gene is a member of the following regulons


CysL regulon

The CysL regulon


Gene


  • Coordinates on the chromosome (coding sequence): 3,864,309 -> 3,865,208
  • Phenotypes of a mutant

  • unable to grow with sulfate or sulfite as the only sulfur source PubMed
  • The protein


    Catalyzed reaction/ biological activity

    Protein family

  • LysR family
  • Paralogous protein(s)

    Kinetic information

    Domains

    Modification

    Cofactors

    Effectors of protein activity

    Structure

    Localization

    Interactions

    Additional information

    Expression and Regulation


    Operon

  • cysL PubMed
  • Sigma factor

  • SigA PubMed
  • Regulation

  • repressed by sulfate, sulfite, and thiosulfate (CysL) PubMed
  • Regulatory mechanism

  • CysL: auto-repression PubMed
  • Additional information

    Biological materials


    Mutant

  • MGNA-B668 (ywfK::erm), available at the NBRP B. subtilis, Japan
  • Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct

    Antibody

    Labs working on this gene/protein


    References


    Guillouard I(1), Auger S, Hullo MF, Chetouani F, Danchin A, Martin-Verstraete I.

    Identification of Bacillus subtilis CysL, a regulator of the cysJI operon, which encodes sulfite reductase.

    J Bacteriol. 2002 Sep;184(17):4681-9.
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