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Categories containing this gene/protein

utilization of specific carbon sources, utilization of nitrogen sources other than amino acids, transcription factors and their control

This gene is a member of the following regulons

The FrlR regulon


  • Coordinates on the chromosome (coding sequence): 3,346,298 -> 3,347,026
  • The protein

    Catalyzed reaction/ biological activity

    Protein family

  • GntR family of transcription factors
  • Paralogous protein(s)

    Kinetic information




    Effectors of protein activity


  • 2IKK (C-terminal domain)
  • Localization


    Additional information

    Expression and Regulation


    Sigma factor


    Regulatory mechanism

    Additional information

    Biological materials


  • MGNA-A557 (yurK::erm), available at the NBRP B. subtilis, Japan
  • Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct


    Labs working on this gene/protein


    Deppe VM, Klatte S, Bongaerts J, Maurer KH, O'Connell T, Meinhardt F

    Genetic control of amadori product degradation in Bacillus subtilis via regulation of frlBONMD expression by FrlR

    Appl Environ Microbiol. 2011 May;77(9):2839-46. doi: 10.1128/AEM.02515-10. Epub 2011 Mar 11. PubMed PMID: 21398478; PubMed Central PMCID: PMC3126415.
    Deppe VM, Bongaerts J, O'Connell T, Maurer KH, Meinhardt F

    Enzymatic deglycation of Amadori products in bacteria: mechanisms, occurrence and physiological functions

    Appl Microbiol Biotechnol. 2011 Apr;90(2):399-406. doi: 10.1007/s00253-010-3083-4. Epub 2011 Feb 24. Review. PubMed PMID: 21347729.
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