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Categories containing this gene/protein

cell wall degradation/ turnover, utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

GamR regulon

The GamR regulon


  • Coordinates on the chromosome (coding sequence): 257,791 -> 258,498
  • The protein

    Catalyzed reaction/ biological activity

    Protein family

  • GntR family of transcription factors
  • Paralogous protein(s)

    Kinetic information




    Effectors of protein activity

  • glucosamine-6-phosphate acts as molecular inducer that prevents GamR from binding to its operator sites in the promoter regions of the gamA-gamP and gamR-ybgB operons PubMed
  • Structure



    Additional information

    Expression and Regulation


  • gamR-ybgB PubMed
  • Sigma factor

  • SigA PubMed
  • Regulation

  • induced by glucosamine (GamR) PubMed
  • Regulatory mechanism

  • GamR: transcription repression PubMed
  • Additional information

    Biological materials


    Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct


    Labs working on this gene/protein



    Plumbridge J(1).

    Regulation of the Utilization of Amino Sugars by Escherichia coli and Bacillus subtilis: Same Genes, Different Control.

    J Mol Microbiol Biotechnol. 2015;25(2-3):154-67. doi: 10.1159/000369583. Epub 2015 Jul 9.DOI: 10.1159/000369583 PMID: 26159076 [Indexed for MEDLINE]

    Original publications

    Gaugué I, Oberto J, Plumbridge J

    Regulation of amino sugar utilization in Bacillus subtilis by the GntR family regulators, NagR and GamR

    Mol Microbiol. 2014 Apr;92(1):100-15. doi: 10.1111/mmi.12544. Epub 2014 Mar 5. PubMed PMID: 24673833.
    Gaugué I, Oberto J, Putzer H, Plumbridge J

    The use of amino sugars by Bacillus subtilis: presence of a unique operon for the catabolism of glucosamine

    PLoS One. 2013 May 8;8(5):e63025. doi: 10.1371/journal.pone.0063025. Print 2013. PubMed PMID: 23667565; PubMed Central PMCID: PMC3648570.
    Reizer J, Bachem S, Reizer A, Arnaud M, Saier MH Jr, Stülke J

    Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis

    Microbiology. 1999 Dec;145 ( Pt 12):3419-29. PubMed PMID: 10627040.
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