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Categories containing this gene/protein


transcription factors and their control

This gene is a member of the following regulons


GltR regulon

The GltR regulon


Gene


  • Coordinates on the chromosome (coding sequence): 2,725,837 -> 2,726,727
  • Phenotypes of a mutant

  • The function of this protein is unknown. However, certain mutant forms are able to activate expression of the gltA-gltB operon (and thus to replace the cognate activator protein GltC)
  • The protein


    Catalyzed reaction/ biological activity

    Protein family

  • LysR family of transcription factors
  • Paralogous protein(s)

    Kinetic information

    Domains

    Modification

    Cofactors

    Effectors of protein activity

    Structure

    Localization

    Interactions

    Additional information

  • The function of this protein is unknown. However, certain mutant forms are able to activate expression of the gltA-gltB operon (and thus to replace the cognate activator protein GltC)
  • Expression and Regulation


    Operon

  • gltR (according to DBTBS)
  • Sigma factor

  • SigA PubMed
  • Regulation

    Regulatory mechanism

  • GltR: negative autoregulation PubMed
  • Additional information

    Biological materials


    Mutant

  • GP345 (erm), available in the Stülke lab
  • Expression vector

  • pBP421 (N-terminal Strep-tag, for SPINE, purification from B. subtilis, in pGP382) (available in Fabian Commichau's lab)
  • lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct

    Antibody

    Labs working on this gene/protein


  • Linc Sonenshein, Tufts University, Boston, MA, USA Homepage
  • References


    Belitsky BR(1), Sonenshein AL.

    Altered transcription activation specificity of a mutant form of Bacillus subtilis GltR, a LysR family member.

    J Bacteriol. 1997 Feb;179(4):1035-43.
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