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Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

The GutR regulon


  • Coordinates on the chromosome (coding sequence): 664,775 -> 667,264
  • The protein

    Catalyzed reaction/ biological activity

    Protein family

    Paralogous protein(s)

    Kinetic information




    Effectors of protein activity




    Additional information

    Expression and Regulation


  • gutR PubMed
  • Sigma factor


    Regulatory mechanism

    Additional information

    Biological materials


    Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct


    Labs working on this gene/protein


    Watanabe S, Hamano M, Kakeshita H, Bunai K, Tojo S, Yamaguchi H, Fujita Y, Wong SL, Yamane K

    Mannitol-1-phosphate dehydrogenase (MtlD) is required for mannitol and glucitol assimilation in Bacillus subtilis: possible cooperation of mtl and gut operons

    J Bacteriol. 2003 Aug;185(16):4816-24. PubMed PMID: 12897001; PubMed Central PMCID: PMC166460.
    Poon KK, Chu JC, Wong SL

    Roles of glucitol in the GutR-mediated transcription activation process in Bacillus subtilis: glucitol induces GutR to change its conformation and to bind ATP

    J Biol Chem. 2001 Aug 10;276(32):29819-25. Epub 2001 Jun 4. PubMed PMID: 11390381.
    Poon KK, Chen CL, Wong SL

    Roles of glucitol in the GutR-mediated transcription activation process in Bacillus subtilis: tight binding of GutR to tis binding site

    J Biol Chem. 2001 Mar 30;276(13):9620-5. Epub 2000 Dec 15. PubMed PMID: 11118449.
    Ye R, Rehemtulla SN, Wong SL

    Glucitol induction in Bacillus subtilis is mediated by a regulatory factor, GutR

    J Bacteriol. 1994 Jun;176(11):3321-7. PubMed PMID: 8195087; PubMed Central PMCID: PMC205503.
    Ye R, Wong SL

    Transcriptional regulation of the Bacillus subtilis glucitol dehydrogenase gene

    J Bacteriol. 1994 Jun;176(11):3314-20. PubMed PMID: 8195086; PubMed Central PMCID: PMC205502.
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