SubtiBank SubtiBank

It will happen very soon:

International Conference on Bacilli and Gram-positive bacteria

June 11 - 15, 2017, Berlin, Germany

Check out the program here

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control, phosphoproteins

This gene is a member of the following regulons

The LicR regulon


  • Coordinates on the chromosome (coding sequence): 3,962,003 -> 3,963,928
  • The protein

    Catalyzed reaction/ biological activity

  • Protein EIIA N(pi)-phospho-L-histidine + protein EIIB = protein EIIA + protein EIIB N(pi)-phospho-L-histidine/cysteine (according to Swiss-Prot)
  • Protein family

  • transcriptional antiterminator bglG family (according to Swiss-Prot), Attention: this is wrong: LicR is a transcription activator, the similarity to the BglG family is limited to the PTS-regulation domains
  • Paralogous protein(s)

    Kinetic information




    Effectors of protein activity




  • LicB-LicR
  • PtsH-LicR
  • Additional information

    Expression and Regulation


  • licR PubMed
  • Sigma factor

  • SigA PubMed
  • Regulation

    Regulatory mechanism

    Additional information

    Biological materials


    Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct


    Labs working on this gene/protein


    Tobisch S, Stülke J, Hecker M

    Regulation of the lic operon of Bacillus subtilis and characterization of potential phosphorylation sites of the LicR regulator protein by site-directed mutagenesis

    J Bacteriol. 1999 Aug;181(16):4995-5003. PubMed PMID: 10438772; PubMed Central PMCID: PMC93989.
    Tobisch S, Glaser P, Krüger S, Hecker M

    Identification and characterization of a new beta-glucoside utilization system in Bacillus subtilis

    J Bacteriol. 1997 Jan;179(2):496-506. PubMed PMID: 8990303; PubMed Central PMCID: PMC178721.
    No login