SubtiBank SubtiBank

Categories containing this gene/protein


Biosynthesis of cofactors

This gene is a member of the following regulons


Gene


  • Coordinates on the chromosome (coding sequence): 1,099,159 -> 1,100,154
  • The protein


    Catalyzed reaction/ biological activity

    Protein family

    Paralogous protein(s)

    Kinetic information

    Domains

    Modification

    Cofactors

    Effectors of protein activity

    Structure

    Localization

    Interactions

    Additional information

    Expression and Regulation


    Operon

    Sigma factor

    Regulation

  • induced by valine PubMed
  • Regulatory mechanism

    Additional information

    Biological materials


    Mutant

    Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct

    Antibody

    Labs working on this gene/protein


    References


    Reviews

    Cronan JE(1).

    Assembly of Lipoic Acid on Its Cognate Enzymes: an Extraordinary and Essential Biosynthetic Pathway.

    Microbiol Mol Biol Rev. 2016 Apr 13;80(2):429-50. doi: 10.1128/MMBR.00073-15. Print 2016 Jun.DOI: 10.1128/MMBR.00073-15 PMCID: PMC4867368 [Available on 2017-04-13] PMID: 27074917 [PubMed - in process]

    Original publications

    Christensen QH, Martin N, Mansilla MC, de Mendoza D, Cronan JE

    A novel amidotransferase required for lipoic acid cofactor assembly in Bacillus subtilis

    Mol Microbiol. 2011 Apr;80(2):350-63. doi: 10.1111/j.1365-2958.2011.07598.x. PubMed PMID: 21338421; PubMed Central PMCID: PMC3088481.
    Martin N, Christensen QH, Mansilla MC, Cronan JE, de Mendoza D

    A novel two-gene requirement for the octanoyltransfer reaction of Bacillus subtilis lipoic acid biosynthesis

    Mol Microbiol. 2011 Apr;80(2):335-49. doi: 10.1111/j.1365-2958.2011.07597.x. PubMed PMID: 21338420; PubMed Central PMCID: PMC3086205.
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