SubtiBank SubtiBank
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Categories containing this gene/protein


transcription factors and their control, resistance against toxins/ antibiotics

This gene is a member of the following regulons


MdtR regulon

The MdtR regulon


Gene


  • Coordinates on the chromosome (coding sequence): 3,374,492 -> 3,374,959
  • The protein


    Catalyzed reaction/ biological activity

    Protein family

    Paralogous protein(s)

    Kinetic information

    Domains

    Modification

    Cofactors

    Effectors of protein activity

    Structure

  • 1S3J
  • Localization

    Interactions

    Additional information

    Expression and Regulation


    Operon

  • mdtR-mdtP PubMed
  • Sigma factor

    Regulation

    Regulatory mechanism

  • repression by MdtR PubMed
  • Additional information

    Biological materials


    Mutant

  • MGNA-B595 (yusO::erm), available at the NBRP B. subtilis, Japan
  • GP1115 (spc), available in Stülke lab
  • Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct

    Antibody

    Labs working on this gene/protein


    References


    Kim JY(1), Inaoka T, Hirooka K, Matsuoka H, Murata M, Ohki R, Adachi Y, Fujita Y, Ochi K.

    Identification and characterization of a novel multidrug resistance operon, mdtRP (yusOP), of Bacillus subtilis.

    J Bacteriol. 2009 May;191(10):3273-81. doi: 10.1128/JB.00151-09. Epub 2009 Mar 13.
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