Categories containing this gene/protein
transcription factors and their control, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)
This gene is a member of the following regulons
Coordinates on the chromosome (coding sequence): 909,198 -> 909,746
Catalyzed reaction/ biological activity
Effectors of protein activityphenolic acid acts as molecular inducer and releases PadR from the yveF-yveG-padC promoter PubMed
Structurecytoplasm (according to Swiss-Prot)
Expression and Regulation
OperonpadR (according to DBTBS)
Regulationweak constitutive expression
MutantMGNA-C303 (yfiO::erm), available at the NBRP B. subtilis, Japan
Labs working on this gene/protein
Nguyen TK, Tran NP, Cavin JF
Genetic and biochemical analysis of PadR-padC
promoter interactions during the phenolic acid stress response in Bacillus
subtilis 168 J Bacteriol. 2011 Aug;193(16):4180-91. doi: 10.1128/JB.00385-11.
PubMed PMID: 21685295; PubMed Central PMCID: PMC3147689.
Tran NP, Gury J, Dartois V, Nguyen TK, Seraut H, Barthelmebs L, Gervais P,
Phenolic acid-mediated regulation of the padC gene, encoding the
phenolic acid decarboxylase of Bacillus subtilis J Bacteriol. 2008
May;190(9):3213-24. doi: 10.1128/JB.01936-07. PubMed PMID: 18326577; PubMed
Central PMCID: PMC2347383.