It will happen very soon:
International Conference on Bacilli and Gram-positive bacteria
June 11 - 15, 2017, Berlin, Germany
Check out the program here
Dear users of SubtiWiki,
We have scheduled the server update on Sunday, 28th May, 2017. The website might be unreachable for a few hours. We appologize for the inconvinience and thank you for your understanding.
We will also use the time to upgrade SubtiWiki to a new version. It is current avaible online. Have a preview at Here
In the coming Bacilli meeting in Berlin, we will be hosting a SubtiWiki workshop, where we will reveal all nnew features as well as the strategies used behind the scene. We sincerely welcomme you to join.
Thank you for your understanding and support.
Your SubtiWiki Team
Categories containing this gene/protein
transcription factors and their control, resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)
This gene is a member of the following regulons
LmrA regulon, QdoR regulon
Coordinates on the chromosome (coding sequence): 4,107,352 -> 4,107,927
Catalyzed reaction/ biological activity
Protein familyTetR family
Effectors of protein activityflavonoids such as quercetin act as molecular inducers and result in release from DNA targets PubMed
Expression and Regulation
Regulationinduced by flavonoids such as quercetin (QdoR, LmrA) PubMed
Regulatory mechanismLmrA: transcription repression PubMedQdoR: transcription repression PubMed
MutantMGNA-B683 (yxaF::erm), available at the NBRP B. subtilis, Japan
Labs working on this gene/protein
Yasutaro Fujita, University of Fukuyama, Japan
Transcriptional response machineries of Bacillus subtilis conducive
to plant growth promotion Biosci Biotechnol Biochem. 2014;78(9):1471-84. doi:
10.1080/09168451.2014.943689. PubMed PMID: 25209494.
Cuthbertson L, Nodwell JR
The TetR family of regulators Microbiol Mol Biol
Rev. 2013 Sep;77(3):440-75. doi: 10.1128/MMBR.00018-13. Review. PubMed PMID:
24006471; PubMed Central PMCID: PMC3811609.
Hirooka K, Fujita Y
Identification of aromatic residues critical to the DNA
binding and ligand response of the Bacillus subtilis QdoR (YxaF) repressor
antagonized by flavonoids Biosci Biotechnol Biochem. 2011;75(7):1325-34. Epub
2011 Jul 7. PubMed PMID: 21737930.
Hirooka K, Kunikane S, Matsuoka H, Yoshida K, Kumamoto K, Tojo S, Fujita Y
Dual regulation of the Bacillus subtilis regulon comprising the lmrAB and yxaGH
operons and yxaF gene by two transcriptional repressors, LmrA and YxaF, in
response to flavonoids J Bacteriol. 2007 Jul;189(14):5170-82. Epub 2007 May 4.
PubMed PMID: 17483215; PubMed Central PMCID: PMC1951842.
Yoshida K, Ishio I, Nagakawa E, Yamamoto Y, Yamamoto M, Fujita Y
study of gene expression and transcription organization in the gntZ-ywaA region
of the Bacillus subtilis genome Microbiology. 2000 Mar;146 ( Pt 3):573-9. PubMed