SubtiBank SubtiBank
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Categories containing this gene/protein


utilization of specific carbon sources, transcription factors and their control, membrane proteins

This gene is a member of the following regulons


RhgR regulon

The RhgR regulon


Gene


  • Coordinates on the chromosome (coding sequence): 765,838 -> 768,123
  • The protein


    Catalyzed reaction/ biological activity

    Protein family

  • AraC family
  • Paralogous protein(s)

    Kinetic information

    Domains

  • HPr-binding domain: aa 406 - 510 PubMed
  • Modification

    Cofactors

    Effectors of protein activity

  • interaction with HPr(His)-P (occurs in the absence of preferred carbon sources) stimulates YesS activity PubMed
  • Structure

    Localization

  • cell membrane (according to Swiss-Prot)
  • Interactions

  • RhgR is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of interactions PubMed
  • HPr(His)-P-RhgR PubMed
  • Additional information

    Expression and Regulation


    Operon

  • rhgR-yesT-yesU-yesV-yesW-yesX-yesY-yesZ PubMed
  • Sigma factor

    Regulation

  • induced by pectin (RhgR) PubMed
  • Regulatory mechanism

  • RhgR: transcriptional activation PubMed
  • Additional information

    Biological materials


    Mutant

  • MGNA-B450 (yesS::erm), available at the NBRP B. subtilis, Japan
  • Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct

    Antibody

    Labs working on this gene/protein


    References


    Rodionova IA, Li X, Thiel V, Stolyar S, Stanton K, Fredrickson JK, Bryant DA, Osterman AL, Best AA, Rodionov DA

    Comparative genomics and functional analysis of rhamnose catabolic pathways and regulons in bacteria

    Front Microbiol. 2013 Dec 23;4:407. doi: 10.3389/fmicb.2013.00407. PubMed PMID: 24391637; PubMed Central PMCID: PMC3870299.
    Marchadier E, Carballido-López R, Brinster S, Fabret C, Mervelet P, Bessières P, Noirot-Gros MF, Fromion V, Noirot P

    An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach

    Proteomics. 2011 Aug;11(15):2981-91. doi: 10.1002/pmic.201000791. PubMed PMID: 21630458.
    Poncet S, Soret M, Mervelet P, Deutscher J, Noirot P

    Transcriptional activator YesS is stimulated by histidine-phosphorylated HPr of the Bacillus subtilis phosphotransferase system

    J Biol Chem. 2009 Oct 9;284(41):28188-97. doi: 10.1074/jbc.M109.046334. PubMed PMID: 19651770; PubMed Central PMCID: PMC2788870.
    Ochiai A, Itoh T, Kawamata A, Hashimoto W, Murata K

    Plant cell wall degradation by saprophytic Bacillus subtilis strains: gene clusters responsible for rhamnogalacturonan depolymerization

    Appl Environ Microbiol. 2007 Jun;73(12):3803-13. PubMed PMID: 17449691; PubMed Central PMCID: PMC1932723.
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