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Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control, membrane proteins

This gene is a member of the following regulons

RhgR regulon

The RhgR regulon


  • Coordinates on the chromosome (coding sequence): 765,838 -> 768,123
  • The protein

    Catalyzed reaction/ biological activity

    Protein family

  • AraC family
  • Paralogous protein(s)

    Kinetic information


  • HPr-binding domain: aa 406 - 510 PubMed
  • Modification


    Effectors of protein activity

  • interaction with HPr(His)-P (occurs in the absence of preferred carbon sources) stimulates YesS activity PubMed
  • Structure


  • cell membrane (according to Swiss-Prot)
  • Interactions

  • RhgR is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of interactions PubMed
  • HPr(His)-P-RhgR PubMed
  • Additional information

    Expression and Regulation


  • rhgR-yesT-yesU-yesV-yesW-yesX-yesY-yesZ PubMed
  • Sigma factor


  • induced by pectin (RhgR) PubMed
  • Regulatory mechanism

  • RhgR: transcriptional activation PubMed
  • Additional information

    Biological materials


  • MGNA-B450 (yesS::erm), available at the NBRP B. subtilis, Japan
  • Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct


    Labs working on this gene/protein


    Rodionova IA, Li X, Thiel V, Stolyar S, Stanton K, Fredrickson JK, Bryant DA, Osterman AL, Best AA, Rodionov DA

    Comparative genomics and functional analysis of rhamnose catabolic pathways and regulons in bacteria

    Front Microbiol. 2013 Dec 23;4:407. doi: 10.3389/fmicb.2013.00407. eCollection 2013. PubMed PMID: 24391637; PubMed Central PMCID: PMC3870299.
    Marchadier E, Carballido-López R, Brinster S, Fabret C, Mervelet P, Bessières P, Noirot-Gros MF, Fromion V, Noirot P

    An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach

    Proteomics. 2011 Aug;11(15):2981-91. doi: 10.1002/pmic.201000791. Epub 2011 May 31. PubMed PMID: 21630458.
    Poncet S, Soret M, Mervelet P, Deutscher J, Noirot P

    Transcriptional activator YesS is stimulated by histidine-phosphorylated HPr of the Bacillus subtilis phosphotransferase system

    J Biol Chem. 2009 Oct 9;284(41):28188-97. doi: 10.1074/jbc.M109.046334. Epub 2009 Aug 3. PubMed PMID: 19651770; PubMed Central PMCID: PMC2788870.
    Ochiai A, Itoh T, Kawamata A, Hashimoto W, Murata K

    Plant cell wall degradation by saprophytic Bacillus subtilis strains: gene clusters responsible for rhamnogalacturonan depolymerization

    Appl Environ Microbiol. 2007 Jun;73(12):3803-13. Epub 2007 Apr 20. PubMed PMID: 17449691; PubMed Central PMCID: PMC1932723.
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