It will happen very soon:
International Conference on Bacilli and Gram-positive bacteria
June 11 - 15, 2017, Berlin, Germany
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Categories containing this gene/protein
utilization of specific carbon sources, transcription factors and their control
This gene is a member of the following regulons
CcpA regulon, PhoP regulon, TreR regulon
Coordinates on the chromosome (coding sequence): 853,556 -> 854,272
Catalyzed reaction/ biological activity
Protein familyGntR family of transcription factors
Effectors of protein activity
Structure2OGG (effector binding domain) PubMed
Expression and Regulation
OperontreP-treA-treR PubMedSigA PubMed
Regulationinduced by trehalose (TreR) PubMedrepressed by glucose (CcpA) PubMedexpressed under conditions of phosphate limitation (PhoP) PubMed
Regulatory mechanismTreR: transcription repression PubMedCcpA: transcription repression PubMedPhoP: transcription activation PubMed
MutantMGNA-C261 (treR::erm), available at the NBRP B. subtilis, Japan
Labs working on this gene/protein
Ujiie H, Matsutani T, Tomatsu H, Fujihara A, Ushida C, Miwa Y, Fujita Y,
Himeno H, Muto A
Trans-translation is involved in the CcpA-dependent tagging and
degradation of TreP in Bacillus subtilis J Biochem. 2009 Jan;145(1):59-66. doi:
10.1093/jb/mvn143. Epub 2008 Oct 30. PubMed PMID: 18977770.
Rezácová P, Krejciríková V, Borek D, Moy SF, Joachimiak A, Otwinowski Z
crystal structure of the effector-binding domain of the trehalose repressor TreR
from Bacillus subtilis 168 reveals a unique quarternary assembly Proteins. 2007
Nov 15;69(3):679-82. PubMed PMID: 17705272; PubMed Central PMCID: PMC2678876.
Bürklen L, Schöck F, Dahl MK
Molecular analysis of the interaction between
the Bacillus subtilis trehalose repressor TreR and the tre operator Mol Gen
Genet. 1998 Oct;260(1):48-55. PubMed PMID: 9829827.
Schöck F, Dahl MK
Analysis of DNA flanking the treA gene of Bacillus subtilis
reveals genes encoding a putative specific enzyme IITre and a potential regulator
of the trehalose operon Gene. 1996 Oct 10;175(1-2):59-63. PubMed PMID: 8917076.
Schöck F, Dahl MK
Expression of the tre operon of Bacillus subtilis 168 is
regulated by the repressor TreR J Bacteriol. 1996 Aug;178(15):4576-81. PubMed
PMID: 8755887; PubMed Central PMCID: PMC178226.