treR

treR
168

transcription repressor of the [gene|BC568649A341B2E6341993EDA4BF52BDE18A3294|treP]-[gene|2EB9E0C492DF57DF683817E31D6DD34D7580E631|treA]-[gene|DC374E280C5A67C138D7EAC43AA66DA63CEF82B6|treR] operon ([wiki|GntR family])

locus
BSU_07820
Molecular weight
27.69 kDa
pI
6.82
Protein length
Gene length
function
regulation of trehalose utilization
product
transcription repressor ([wiki|GntR family])
essential
no
synonyms
treR, yfxA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2188 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
853,556 → 854,272
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The protein
Protein family
[wiki|GntR family] of transcription factors
[wiki|Domains]
[wiki|HTH gntR-type domain] (aa 1-71) (according to UniProt)
Structure
[PDB|2OGG] (effector binding domain) [Pubmed|17705272]
[AF|P39796]
Expression and Regulation
Operons
genes
[gene|BC568649A341B2E6341993EDA4BF52BDE18A3294|treP]-[gene|2EB9E0C492DF57DF683817E31D6DD34D7580E631|treA]-[gene|DC374E280C5A67C138D7EAC43AA66DA63CEF82B6|treR]
description
[Pubmed|8755887]
regulation
expressed under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|21636651]
regulatory mechanism
[protein|DC374E280C5A67C138D7EAC43AA66DA63CEF82B6|treR]: repression, [Pubmed|8755887], in [regulon|protein:DC374E280C5A67C138D7EAC43AA66DA63CEF82B6|treR regulon]
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|18977770], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|phoP]: activation, [Pubmed|21636651], in [regulon|protein:638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|phoP regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8755887], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|BC568649A341B2E6341993EDA4BF52BDE18A3294|treP]→[gene|DC374E280C5A67C138D7EAC43AA66DA63CEF82B6|treR]

2024-02-29 20:40:26

ghost

46

5ea0c439875fc22b9a05971658c7c0a460d25052

9C91E3C2B12C6666EE92EE6C971F82C82DDCB383

Biological materials
Mutant
MGNA-C261 (treR::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2259 NBRP B. subtilis, Japan]
BKE07820 (Δ[gene|DC374E280C5A67C138D7EAC43AA66DA63CEF82B6|treR]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE07820 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATGGACCACCCAGCTT,  downstream forward: _UP4_TGAGAGAGGCGCCTGCCTGC
BKK07820 (Δ[gene|DC374E280C5A67C138D7EAC43AA66DA63CEF82B6|treR]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK07820 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTATGGACCACCCAGCTT,  downstream forward: _UP4_TGAGAGAGGCGCCTGCCTGC
References
8755887,9829827,8917076,17705272,18977770

DC374E280C5A67C138D7EAC43AA66DA63CEF82B6

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Time of last update: 2024-03-28 19:40:30

Author of last update: Jstuelk