SubtiBank SubtiBank

Categories containing this gene/protein

transporters/ other, membrane proteins

This gene is a member of the following regulons

LexA regulon


  • Coordinates on the chromosome (coding sequence): 609,388 -> 612,045
  • The protein

    Catalyzed reaction/ biological activity

    Protein family

  • mmpL family (according to Swiss-Prot)
  • Paralogous protein(s)

    Kinetic information




    Effectors of protein activity



  • cell membrane (according to Swiss-Prot)
  • Interactions

  • YdgH is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of interactions PubMed
  • Additional information

    Expression and Regulation


  • ydgG-ydgH PubMed
  • Sigma factor


  • induced by DNA damage (LexA) PubMed
  • Regulatory mechanism

  • LexA: transcription repression PubMed
  • Additional information

    Biological materials


  • MGNA-C161 (ydgH::erm), available at the NBRP B. subtilis, Japan
  • Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct


    Labs working on this gene/protein


    Marchadier E, Carballido-López R, Brinster S, Fabret C, Mervelet P, Bessières P, Noirot-Gros MF, Fromion V, Noirot P

    An expanded protein-protein interaction network in Bacillus subtilis reveals a group of hubs: Exploration by an integrative approach

    Proteomics. 2011 Aug;11(15):2981-91. doi: 10.1002/pmic.201000791. PubMed PMID: 21630458.
    Au N, Kuester-Schoeck E, Mandava V, Bothwell LE, Canny SP, Chachu K, Colavito SA, Fuller SN, Groban ES, Hensley LA, O'Brien TC, Shah A, Tierney JT, Tomm LL, O'Gara TM, Goranov AI, Grossman AD, Lovett CM

    Genetic composition of the Bacillus subtilis SOS system

    J Bacteriol. 2005 Nov;187(22):7655-66. PubMed PMID: 16267290; PubMed Central PMCID: PMC1280312.
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