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Categories containing this gene/protein

transcription factors and their control, membrane proteins, phosphoproteins

This gene is a member of the following regulons

YrkP regulon

The YrkP regulon


  • Coordinates on the chromosome (coding sequence): 2,704,435 -> 2,705,130
  • The protein

    Catalyzed reaction/ biological activity

    Protein family

  • OmpR family of two-component response regulators
  • Paralogous protein(s)

    Kinetic information



  • phosphorylated by YrkQ on an Asp residue
  • Cofactors

    Effectors of protein activity

  • phosphorylation likely affects DNA-binding activity
  • Structure



    Additional information

    Expression and Regulation


  • yrkP-yrkQ-yrkR PubMed
  • Sigma factor


    Regulatory mechanism

  • YrkP: transcription activation PubMed
  • Additional information

    Biological materials


    Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct


    Labs working on this gene/protein


    Leyn SA, Kazanov MD, Sernova NV, Ermakova EO, Novichkov PS, Rodionov DA

    Genomic reconstruction of the transcriptional regulatory network in Bacillus subtilis

    J Bacteriol. 2013 Jun;195(11):2463-73. doi: 10.1128/JB.00140-13. Epub 2013 Mar 15. PubMed PMID: 23504016; PubMed Central PMCID: PMC3676070.
    Ogura M, Ohsawa T, Tanaka T

    Identification of the sequences recognized by the Bacillus subtilis response regulator YrkP

    Biosci Biotechnol Biochem. 2008 Jan;72(1):186-96. Epub 2008 Jan 7. PubMed PMID: 18175906.
    Fabret C, Feher VA, Hoch JA

    Two-component signal transduction in Bacillus subtilis: how one organism sees its world

    J Bacteriol. 1999 Apr;181(7):1975-83. Review. PubMed PMID: 10094672; PubMed Central PMCID: PMC93607.
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