It will happen very soon:
International Conference on Bacilli and Gram-positive bacteria
June 11 - 15, 2017, Berlin, Germany
Check out the program here
Dear users of SubtiWiki,
We have scheduled the server update on Sunday, 28th May, 2017. The website might be unreachable for a few hours. We appologize for the inconvinience and thank you for your understanding.
We will also use the time to upgrade SubtiWiki to a new version. It is current avaible online. Have a preview at Here
In the coming Bacilli meeting in Berlin, we will be hosting a SubtiWiki workshop, where we will reveal all nnew features as well as the strategies used behind the scene. We sincerely welcomme you to join.
Thank you for your understanding and support.
Your SubtiWiki Team
Categories containing this gene/protein
transcription factors and their control, cold stress proteins, resistance against toxins/ antibiotics
This gene is a member of the following regulons
Coordinates on the chromosome (coding sequence): 3,118,847 -> 3,119,239
Catalyzed reaction/ biological activity
Protein familyGntR family of transcription factors
Effectors of protein activity
Structure3NEU (similar protein from Listeria innocua, 41% identity)
Expression and Regulation
OperonytrG-ytrA-ytrB-ytrC-ytrD-ytrE-ytrF PubMedSigA PubMed
Regulationinduced by ramoplanin (YtrA) PubMedexpressed early in the stationary phase PubMedinduced by cold shock (5-fold) PubMed
Regulatory mechanismYtrA: transcription repression PubMed
MutantMGNA-A138 (ytrA::erm), available at the NBRP B. subtilis, Japan
Labs working on this gene/protein
Leyn SA, Kazanov MD, Sernova NV, Ermakova EO, Novichkov PS, Rodionov DA
Genomic reconstruction of the transcriptional regulatory network in Bacillus
subtilis J Bacteriol. 2013 Jun;195(11):2463-73. doi: 10.1128/JB.00140-13. Epub
2013 Mar 15. PubMed PMID: 23504016; PubMed Central PMCID: PMC3676070.
Salzberg LI, Luo Y, Hachmann AB, Mascher T, Helmann JD
The Bacillus subtilis
GntR family repressor YtrA responds to cell wall antibiotics J Bacteriol. 2011
Oct;193(20):5793-801. doi: 10.1128/JB.05862-11. Epub 2011 Aug 19. PubMed PMID:
21856850; PubMed Central PMCID: PMC3187214.
Beckering CL, Steil L, Weber MH, Völker U, Marahiel MA
transcriptional analysis of the cold shock response in Bacillus subtilis J
Bacteriol. 2002 Nov;184(22):6395-402. PubMed PMID: 12399512; PubMed Central
Yoshida KI, Fujita Y, Ehrlich SD
An operon for a putative ATP-binding
cassette transport system involved in acetoin utilization of Bacillus subtilis J
Bacteriol. 2000 Oct;182(19):5454-61. PubMed PMID: 10986249; PubMed Central PMCID: