SubtiBank SubtiBank

Categories containing this gene/protein

ABC transporters, cold stress proteins, membrane proteins

This gene is a member of the following regulons

YtrA regulon


  • Coordinates on the chromosome (coding sequence): 3,113,979 -> 3,115,289
  • The protein

    Catalyzed reaction/ biological activity

    Protein family

  • ABC-4 integral membrane protein family (according to Swiss-Prot)
  • Paralogous protein(s)

    Kinetic information




    Effectors of protein activity



  • cell membrane (via YtrC-YtrD) PubMed
  • Interactions

  • (YtrB-YtrE)-(YtrC-YtrD)-YtrF PubMed
  • Additional information

    Expression and Regulation


  • ytrG-ytrA-ytrB-ytrC-ytrD-ytrE-ytrF PubMed
  • Sigma factor

  • SigA PubMed
  • Regulation

  • induced by ramoplanin (YtrA) PubMed
  • expressed early in the stationary phase PubMed
  • induced by cold shock (7.5-fold) PubMed
  • Regulatory mechanism

  • YtrA: transcription repression PubMed
  • Additional information

    Biological materials


  • MGNA-A132 (ytrF::erm), available at the NBRP B. subtilis, Japan
  • Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct


    Labs working on this gene/protein


    Beckering CL, Steil L, Weber MH, Völker U, Marahiel MA

    Genomewide transcriptional analysis of the cold shock response in Bacillus subtilis

    J Bacteriol. 2002 Nov;184(22):6395-402. PubMed PMID: 12399512; PubMed Central PMCID: PMC151959.
    Yoshida KI, Fujita Y, Ehrlich SD

    An operon for a putative ATP-binding cassette transport system involved in acetoin utilization of Bacillus subtilis

    J Bacteriol. 2000 Oct;182(19):5454-61. PubMed PMID: 10986249; PubMed Central PMCID: PMC110989.
    Quentin Y, Fichant G, Denizot F

    Inventory, assembly and analysis of Bacillus subtilis ABC transport systems

    J Mol Biol. 1999 Apr 2;287(3):467-84. PubMed PMID: 10092453.
    No login