It will happen very soon:
International Conference on Bacilli and Gram-positive bacteria
June 11 - 15, 2017, Berlin, Germany
Check out the program here
Scheduled server maintanence and database upgrade on Sunday, 28th May, 2017. Click to see more information
Dear users of
We have scheduled the server update on
Sunday, 28th May, 2017. The website might be unreachable for a few hours. We appologize for the inconvinience and thank you for your understanding.
We will also use the time to upgrade
SubtiWiki to a new version. It is current avaible online. Have a preview at Here
In the coming Bacilli meeting in Berlin, we will be hosting a
SubtiWiki workshop, where we will reveal all nnew features as well as the strategies used behind the scene. We sincerely welcomme you to join.
Thank you for your understanding and support.
Description: two-component response regulator (OmpR family)
(e.g. 10000 or 10,000)
Categories containing this gene/protein
transcription factors and their control, phosphoproteins
This gene is a member of the following regulons
Coordinates on the chromosome (coding sequence): 3,408,353 -> 3,409,066 Phenotypes of a mutant unusual autolysis and higher susceptibility to cell envelope antibiotics (bacitracin, aztreonam, cefepime, fosfomycin) PubMed The protein
Catalyzed reaction/ biological activity transcription activator PubMed Protein family OmpR family of two-component response regulators Paralogous protein(s) Kinetic information Modification phosphorylation (Asp) by YvrG PubMed Effectors of protein activity phosphorylation likely affects DNA-binding activity Structure cytoplasm (according to Swiss-Prot) YvrG- YvrHb PubMed Additional information Expression and Regulation
Operon Regulation Regulatory mechanism Additional information Biological materials
Mutant MGNA-B050 (yvrH::erm), available at the NBRP B. subtilis, Japan Expression vector lacZ fusion GFP fusion two-hybrid system FLAG-tag construct Antibody Labs working on this gene/protein
Salzberg LI, Helmann JD Phenotypic and transcriptomic characterization of
Bacillus subtilis mutants with grossly altered membrane composition J Bacteriol.
2008 Dec;190(23):7797-807. doi: 10.1128/JB.00720-08. Epub 2008 Sep 26. PubMed
PMID: 18820022; PubMed Central PMCID: PMC2583605. Serizawa M, Kodama K, Yamamoto H, Kobayashi K, Ogasawara N, Sekiguchi J
Functional analysis of the YvrGHb two-component system of Bacillus subtilis:
identification of the regulated genes by DNA microarray and northern blot
analyses Biosci Biotechnol Biochem. 2005 Nov;69(11):2155-69. PubMed PMID:
16306698. Fabret C, Feher VA, Hoch JA Two-component signal transduction in Bacillus
subtilis: how one organism sees its world J Bacteriol. 1999 Apr;181(7):1975-83.
Review. PubMed PMID: 10094672; PubMed Central PMCID: PMC93607.