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Categories containing this gene/protein


transcription factors and their control, biofilm formation

This gene is a member of the following regulons


The YwcC regulon


Gene


  • Coordinates on the chromosome (coding sequence): 3,922,292 -> 3,922,963
  • The protein


    Catalyzed reaction/ biological activity

    Protein family

  • TetR family
  • Paralogous protein(s)

    Kinetic information

    Domains

    Modification

    Cofactors

    Effectors of protein activity

    Structure

    Localization

    Interactions

    Additional information

    Expression and Regulation


    Operon

  • ywcC-gtcA-galK-galT PubMed
  • Sigma factor

    Regulation

    Regulatory mechanism

    Additional information

    Biological materials


    Mutant

  • MGNA-B230 (ywcC::erm), available at the NBRP B. subtilis, Japan
  • Expression vector

    lacZ fusion

    GFP fusion

    two-hybrid system

    FLAG-tag construct

    Antibody

    Labs working on this gene/protein


    References


    Reviews

    Cuthbertson L(1), Nodwell JR.

    The TetR family of regulators.

    Microbiol Mol Biol Rev. 2013 Sep;77(3):440-75. doi: 10.1128/MMBR.00018-13.

    Original publications

    Yu Y, Yan F, Chen Y, Jin C, Guo JH, Chai Y

    Poly-γ-Glutamic Acids Contribute to Biofilm Formation and Plant Root Colonization in Selected Environmental Isolates of Bacillus subtilis

    Front Microbiol. 2016 Nov 10;7:1811. eCollection 2016. PubMed PMID: 27891125; PubMed Central PMCID: PMC5102903.
    Chai Y, Beauregard PB, Vlamakis H, Losick R, Kolter R

    Galactose metabolism plays a crucial role in biofilm formation by Bacillus subtilis

    MBio. 2012 Aug 14;3(4):e00184-12. doi: 10.1128/mBio.00184-12. Print 2012. Erratum in: MBio. 2013;4(1). doi:10.1128/mBio.00555-12. PubMed PMID: 22893383; PubMed Central PMCID: PMC3419520.
    Nicolas P, Mäder U, Dervyn E, Rochat T, Leduc A, Pigeonneau N, Bidnenko E, Marchadier E, Hoebeke M, Aymerich S, Becher D, Bisicchia P, Botella E, Delumeau O, Doherty G, Denham EL, Fogg MJ, Fromion V, Goelzer A, Hansen A, Härtig E, Harwood CR, Homuth G, Jarmer H, Jules M, Klipp E, Le Chat L, Lecointe F, Lewis P, Liebermeister W, March A, Mars RA, Nannapaneni P, Noone D, Pohl S, Rinn B, Rügheimer F, Sappa PK, Samson F, Schaffer M, Schwikowski B, Steil L, Stülke J, Wiegert T, Devine KM, Wilkinson AJ, van Dijl JM, Hecker M, Völker U, Bessières P, Noirot P

    Condition-dependent transcriptome reveals high-level regulatory architecture in Bacillus subtilis

    Science. 2012 Mar 2;335(6072):1103-6. doi: 10.1126/science.1206848. PubMed PMID: 22383849.
    Chai Y, Kolter R, Losick R

    Paralogous antirepressors acting on the master regulator for biofilm formation in Bacillus subtilis

    Mol Microbiol. 2009 Nov;74(4):876-87. doi: 10.1111/j.1365-2958.2009.06900.x. Epub 2009 Sep 28. PubMed PMID: 19788541; PubMed Central PMCID: PMC2805041.
    Kobayashi K

    SlrR/SlrA controls the initiation of biofilm formation in Bacillus subtilis

    Mol Microbiol. 2008 Sep;69(6):1399-410. doi: 10.1111/j.1365-2958.2008.06369.x. Epub 2008 Jul 18. PubMed PMID: 18647168.
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