efeU

efeU
168

elemental iron uptake system (permease), high affinity uptake of ferric iron (Fe(III))

locus
BSU_38280
Molecular weight
52.24 kDa
pI
8.96
Protein length
Gene length
function
elemental iron uptake
product
elemental iron uptake system (permease)
essential
no
synonyms
efeU, ywbL

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0672 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,929,105  3,930,550
Phenotypes of a mutant
no growth with ferric iron (Fe3+) as the sole source of iron [pubmed|23764491]
Visit Sartorius.com Visit Sartorius.com
Advertisement
The protein
Protein family
Oxidase-dependent Fe transporter (OFeT) (TC 9.A.10.1) family (single member, according to UniProt)
Structure
[AF|P39595]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|3BED98E311EF380AE77327C7F0A83254805089C0|efeU]-[gene|B31884DC49684A276D65E21A5F59AFDADEB9749C|efeO]-[gene|3985F88334D7B034A66473C5BB39188AB61A65F6|efeB]
description
[Pubmed|9353933]
regulation
immediately induced upon iron starvation (first wave to allow iron uptake) ([protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur]) [Pubmed|29133393,12354229]
regulatory mechanism
[protein|F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur]: repression, [pubmed|12354229], in [regulon|protein:F899F1EE27E6D503BCC06BC52E3C7FD80B8EF725|fur regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|23764491], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Open in new tab

[gene|3BED98E311EF380AE77327C7F0A83254805089C0|efeU]→[gene|3985F88334D7B034A66473C5BB39188AB61A65F6|efeB]

2024-03-24 18:03:32

Jstuelk

78

2df6f8b75b6dc01eab7622f9ec49df472f6aad6f

0A342568538EE157691477116B943A8E96AC21D0

Biological materials
Mutant
MGNA-B226 (ywbL::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1225 NBRP B. subtilis, Japan]
BKE38280 ([gene|3BED98E311EF380AE77327C7F0A83254805089C0|efeU]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38280 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCATGTTCCTCCTATAAT,  downstream forward: _UP4_ACAAACGGAAAGGAACTGAC
BKK38280 ([gene|3BED98E311EF380AE77327C7F0A83254805089C0|efeU]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38280 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCATGTTCCTCCTATAAT,  downstream forward: _UP4_ACAAACGGAAAGGAACTGAC
References
16672620,23180473,12354229,23764491,27795321,29133393

3BED98E311EF380AE77327C7F0A83254805089C0

Page visits: 3551

Time of last update: 2024-03-28 20:01:35

Author of last update: Jstuelk