gtcA
168
flippase, transports the glucose-phosphate moiety of C55-P-Glc across the membrane, teichoic acid glycosylation protein
locus
BSU_38210
Molecular weight
14.21 kDa
pI
8.5
function
glycosylation of teichoic acids
product
flippase for teichoic acid glycosylation
essential
no
synonyms
gtcA, ywcD, ipa-34d, gtaC
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2246 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,921,891 → 3,922,274
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The protein
Protein family
GtrA family (with [protein|CBCBF948979D9D63CBA86A9ED865E43B1F85A0AD|yngA], according to UniProt)
Structure
[AF|P39602]
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|C3D87DAA8DB124D50D2C2B2D424C9608C0DE067F|ywcC]-[gene|FD30C4E458E63E8D6A932B351D4224F1AACD4B1B|gtcA]-[gene|36930CC6FDFCA23D43E264FEA375B78A1434E1BD|galK]-[gene|591428EA1C3D40322BB942429607AF61A90BAF41|galT]
description
[Pubmed|22383849,22893383]
regulation
repressed by glucose ([protein|search|CcpA]) [Pubmed|10666464]
Biological materials
Mutant
MGNA-B231 (ywcD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1230 NBRP B. subtilis, Japan]
BKE38210 (Δ[gene|FD30C4E458E63E8D6A932B351D4224F1AACD4B1B|gtcA]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE38210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATTATTTCTCTATACT, downstream forward: _UP4_TGAGAGGACTGCAGCATATG
BKK38210 (Δ[gene|FD30C4E458E63E8D6A932B351D4224F1AACD4B1B|gtcA]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK38210 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATAATTATTTCTCTATACT, downstream forward: _UP4_TGAGAGGACTGCAGCATATG
References
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Time of last update: 2024-04-23 09:48:45
Author of last update: Jstuelk