gutP
168
glucitol permease
locus
BSU_06160
Molecular weight
51.59 kDa
pI
9.81
function
glucitol uptake
product
glucitol permease
essential
no
synonyms
gutP, ydjD
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2211 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
668,601 → 669,992
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The protein
Protein family
[wiki|sodium:galactoside symporter (TC 2.A.2) family] (according to UniProt)
Structure
[PDB|4M64] (melibiose permease from Salmonella typhimurium, 31% identity) [pubmed|24389923]
[AF|O34368]
Paralogous protein(s)
[protein|F92925E2FDCFE6DDA3E87C7B541FE6A6CE5AABB8|xynP], [protein|59CD3E4C24326542D9C85BB6FE64FBF49869EB55|yjmB]
Expression and Regulation
Operons
genes
[gene|2E9D10B0FA5685800007222A5AAD71E975675DB1|gutB]-[gene|B13F7C35FBD55C674E5B19836D32279E7C1A5520|gutP]-[gene|0C4F0C9EF18FB4E9BB5BC3F53F7DDF5F32B51FA5|fruC]
description
[Pubmed|22383849]
regulation
induced by glucitol ([protein|926BCA197F259558F72FDCC73998497B9B167D22|gutR]) [Pubmed|8195086]
regulatory mechanism
[protein|926BCA197F259558F72FDCC73998497B9B167D22|gutR]: activation, [Pubmed|8195086], in [regulon|protein:926BCA197F259558F72FDCC73998497B9B167D22|gutR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|8195086], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
Biological materials
Mutant
MGNA-C212 (ydjD::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2210 NBRP B. subtilis, Japan]
BKE06160 (Δ[gene|B13F7C35FBD55C674E5B19836D32279E7C1A5520|gutP]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE06160 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCATTTCCCACCCCAAGA, downstream forward: _UP4_TAAATAGATGTAAAATTTTT
BKK06160 (Δ[gene|B13F7C35FBD55C674E5B19836D32279E7C1A5520|gutP]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK06160 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCATTTCCCACCCCAAGA, downstream forward: _UP4_TAAATAGATGTAAAATTTTT
References
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Time of last update: 2024-04-15 22:35:09
Author of last update: Jstuelk