malL
168
alpha-glucosidase
locus
BSU_34560
Molecular weight
65.91 kDa
pI
4.98
function
starch and maltodextrin utilization
product
alpha-glucosidase
essential
no
ec
3.2.1.10
synonyms
malL, yvdL
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG0366 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
3,547,550 3,549,235
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The protein
Catalyzed reaction/ biological activity
Hydrolysis of (1->6)-alpha-D-glucosidic linkages in some oligosaccharides produced from starch and glycogen by alpha-amylase, and in isomaltose (according to UniProt)
Protein family
[wiki|glycosyl hydrolase 13 family] (according to UniProt)
Structure
[PDB|1UOK] (from ''Bacillus cereus'', 57% identity, 74% similarity)\t[Pubmed|9193006]
[AF|O06994]
Paralogous protein(s)
[protein|A641BA91317CBCFE34A2BE69007247F209075095|ycdG], [protein|A9500B1E45CCE51F4A699E4A7BC1F6B272A25A86|yugT], [protein|2EB9E0C492DF57DF683817E31D6DD34D7580E631|treA]
[wiki|Localization]
cytoplasm (according to Swiss-Prot)
Expression and Regulation
Operons
genes
[gene|EA1BEC9FCFD2A32142A8A8E6D7362DB37E02052A|mdxR]-[gene|A577441DE4ABAF624D507DB80FBED2A652BCF385|yvdF]-[gene|5771E1976D986638B13ADDE97EDE32709E355923|mdxE]-[gene|EA2DD9892C1128ADCD6C8BC61248EBE45339E6D6|mdxF]-[gene|D72CFFE8ED3EC0280AE92C05A136D66ED1F62251|mdxG]-[gene|68C6FD5D4D9491EE15A5015447959A45C36EA702|yvdJ]-[gene|5F615BB886EC4F7000AAD42258DB8E47616552DE|yvdK]-[gene|6E5AB4620F9A896C32CD77AF314C67035814AE0A|malL]-[gene|CAFAE305B1771DD89E81F75A6713161393BE99A0|pgcM]
description
[Pubmed|16707683]
regulation
induced in the presence of starch, β-cyclomaltodextrin, or maltose [Pubmed|36723711,9573215]
regulatory mechanism
[protein|EA1BEC9FCFD2A32142A8A8E6D7362DB37E02052A|mdxR]: activation, [pubmed|36723711], in [regulon|protein:EA1BEC9FCFD2A32142A8A8E6D7362DB37E02052A|mdxR regulon]
Biological materials
Mutant
BKE34560 ([gene|6E5AB4620F9A896C32CD77AF314C67035814AE0A|malL]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE34560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATAAACGACAGCTTCTTTCC, downstream forward: _UP4_GAAGCTGTGATGGGCATTAG
BKK34560 ([gene|6E5AB4620F9A896C32CD77AF314C67035814AE0A|malL]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK34560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_ATAAACGACAGCTTCTTTCC, downstream forward: _UP4_GAAGCTGTGATGGGCATTAG
References
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Time of last update: 2024-04-19 01:44:12
Author of last update: Jstuelk