ylmC
168
sporulation protein
locus
BSU_15360
Molecular weight
8.62 kDa
pI
5.64
function
unknown
product
sporulation protein
essential
no
synonyms
ylmC, thiQ
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1873 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,608,919 1,609,164
Phenotypes of a mutant
a ''[gene|1D27C5E73571A737B80649BFCF517C5FF136DFFF|ylmC] [gene|AC541AB15B4A2BC345B471BD654299BAEC3E8635|ymxH]'' double mutant has a severe [wiki|sporulation] defect (1% sporulation as compared to the wild type or single mutants), the block is at stage III of [wiki|sporulation] [Pubmed|23396918]
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The protein
Protein family
YlmC/YmxH family (with [protein|AC541AB15B4A2BC345B471BD654299BAEC3E8635|ymxH], according to UniProt)
Structure
[AF|O31725]
Paralogous protein(s)
[protein|AC541AB15B4A2BC345B471BD654299BAEC3E8635|ymxH]
Expression and Regulation
Operons
genes
[gene|1D27C5E73571A737B80649BFCF517C5FF136DFFF|ylmC]
description
[pubmed|22383849]
regulatory mechanism
[protein|90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID]: repression, in [regulon|protein:90DCE4F286D2C151D8BDBF0E024E6BBEC94E2397|spoIIID regulon]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
Biological materials
Mutant
MGNA-B170 (ylmC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1169 NBRP B. subtilis, Japan]
BKE15360 ([gene|1D27C5E73571A737B80649BFCF517C5FF136DFFF|ylmC]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE15360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCATCACGTCCTTTTT, downstream forward: _UP4_TAAACCTGCTTGTCTGCCGC
BKK15360 ([gene|1D27C5E73571A737B80649BFCF517C5FF136DFFF|ylmC]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK15360 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTCCATCACGTCCTTTTT, downstream forward: _UP4_TAAACCTGCTTGTCTGCCGC
References
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Time of last update: 2024-04-14 16:34:14
Author of last update: Jstuelk