xylB

xylB
168

xylulokinase

locus
BSU_17610
Molecular weight
55.25 kDa
pI
6.46
Protein length
Gene length
function
utilization of xylan and xylose
product
xylulokinase
essential
no
ec
2.7.1.17
synonyms
xylB, yncA

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1070 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,893,396 → 1,894,895
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The protein
Catalyzed reaction/ biological activity
ATP + D-xylulose --> ADP + D-xylulose 5-phosphate + H+ (according to UniProt)
Protein family
[wiki|FGGY kinase family] (according to UniProt)
Structure
[PDB|2NLX] (from ''E. coli'', 35% identity, 52% similarity) [Pubmed|17123542]
[AF|P39211]
Expression and Regulation
Operons
genes
[gene|24829427B4518FE67038F194B54D4AAFAC64EF19|xylA]-[gene|F417A5B46CC7FC69DC8606A46D1AD5E41FA35B13|xylB]
description
[Pubmed|1921970]
regulation
carbon catabolite repression ([protein|search|CcpA]) [Pubmed|8132469]
regulatory mechanism
[protein|E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA]: repression, [Pubmed|8132469], in [regulon|protein:E39AFEB7B7F28969A35C4B51CC6E7819F71C79D9|ccpA regulon]
[protein|AF4395D134485290F4AA307B48494FED39E52CD7|xylR]: repression, [Pubmed|2454911], in [regulon|protein:AF4395D134485290F4AA307B48494FED39E52CD7|xylR regulon]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA]: sigma factor, [Pubmed|2454911], in [regulon|protein:360F48D576DE950DF79C1A2677B7A35A8D8CC30C|sigA regulon]
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[gene|24829427B4518FE67038F194B54D4AAFAC64EF19|xylA]→[gene|F417A5B46CC7FC69DC8606A46D1AD5E41FA35B13|xylB]

2024-03-06 21:09:56

ghost

60

03ab48d2da7656afb5bebb25c49c9a7a060c0932

CFA5B475783918BA5946A0FB73EFAFE093A8416B

Biological materials
Mutant
GP1151 (del aphA3) available in [wiki|Stülke] lab
1A719 (no resistance), [Pubmed|1719948], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A719&Search=1A719 BGSC]
BKE17610 (Δ[gene|F417A5B46CC7FC69DC8606A46D1AD5E41FA35B13|xylB]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE17610 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTTTCACTCCTTGCCC,  downstream forward: _UP4_TAATGATGTTATTGTCTGGA
BKK17610 (Δ[gene|F417A5B46CC7FC69DC8606A46D1AD5E41FA35B13|xylB]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK17610 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATTTTTTCACTCCTTGCCC,  downstream forward: _UP4_TAATGATGTTATTGTCTGGA
labs
[wiki|Wolfgang Hillen], Erlangen University, Germany [http://www.biologie.uni-erlangen.de/mibi/index2.html Homepage]
References
17123542,1921970,2454911,8132469

F417A5B46CC7FC69DC8606A46D1AD5E41FA35B13

Page visits: 3364

Time of last update: 2024-03-29 09:51:36

Author of last update: Melvin.boenninger