yitC

yitC
168

mother cell-specific [wiki|sporulation] protein, similar to 2-phosphosulfolactate phosphatase

locus
BSU_10940
Molecular weight
24.51 kDa
pI
5.22
Protein length
Gene length
function
unknown
product
unknown
essential
no
synonyms
yitC

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2045 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
1,172,650 → 1,173,336
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The protein
Catalyzed reaction/ biological activity
(2R)-O-phospho-3-sulfolactate + H2O --> (R)-3-sulfolactate + phosphate (according to UniProt)
Protein family
ComB family (single member, according to UniProt)
Structure
[PDB|1VR0] (from Clostridium acetobutylicum, 31% identity) [pubmed|16927339]
[AF|O06738]
Additional information
The gene is annotated in KEGG as ortholog of 2-phosphosulfolactate phosphatase EC 3.1.3.71. In Swiss-Prot the protein is marked as “probable 2-phosphosulfolactate phosphatase”. No EC annotation is available in MeMetaCyc.No literature/experimental evidence supporting the annotation is available. [Pubmed|19935659]
Expression and Regulation
Operons
genes
[gene|FA7147930DA90604BE2B4837A8A4393F72498AB1|yitC]-[gene|97156E7227E298B0DECC9AAC1411D0DAF3420C29|yitD]
description
[Pubmed|22383849]
regulation
expressed during [wiki|sporulation] in the mother cell ([protein|search|SigE], [protein|search|SigK]) [Pubmed|15699190,15383836]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE]: sigma factor, [Pubmed|15383836], in [regulon|protein:3CB24D493B3282278B7DC61CE3C793DFA815F9E2|sigE regulon]
[protein|24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK]: sigma factor, [Pubmed|15699190,15383836], in [regulon|protein:24F7FD5C7C3A68BB2760ABB8CBD8FBD65E5FF7D4|sigK regulon]
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[gene|FA7147930DA90604BE2B4837A8A4393F72498AB1|yitC]→[gene|97156E7227E298B0DECC9AAC1411D0DAF3420C29|yitD]

2024-02-06 06:53:38

ghost

30

ad2c7d1e628ef8018acb407596e904e7227b3b19

88CAA5C4794C71F1F27E2409BD1A24A4FE274C55

Biological materials
Mutant
MGNA-B177 (yitC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1176 NBRP B. subtilis, Japan]
BKE10940 (Δ[gene|FA7147930DA90604BE2B4837A8A4393F72498AB1|yitC]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE10940 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATACTACCTCTCCTTGGGC,  downstream forward: _UP4_CCAACGATAGAGAGGGTCAT
BKK10940 (Δ[gene|FA7147930DA90604BE2B4837A8A4393F72498AB1|yitC]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK10940 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATACTACCTCTCCTTGGGC,  downstream forward: _UP4_CCAACGATAGAGAGGGTCAT
References
15699190,15383836,27766092,16927339

FA7147930DA90604BE2B4837A8A4393F72498AB1

Page visits: 2913

Time of last update: 2024-03-28 01:43:50

Author of last update: Melvin.boenninger