yknU
168
similar to [wiki|ABC transporter] (ATP-binding protein)
locus
BSU_14320
Molecular weight
66.08 kDa
pI
9.39
function
unknown
product
[wiki|ABC transporter] (ATP-binding protein)
essential
no
synonyms
yknU
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG1132 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
1,499,889 1,501,646
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The protein
Protein family
[wiki|ABC transporter superfamily] (according to UniProt)
[wiki|Domains]
has both a membrane-spanning and an ATP-binding domain [Pubmed|10092453]
[wiki|ABC transmembrane type-1 domain] (aa 18-301) (according to UniProt)
[wiki|ABC transporter domain] (aa 335-570) (according to UniProt)
Structure
[PDB|5MKK] (TmrAB complex from Thermus thermophilus, 37% identity) [pubmed|28069938]
[AF|O31707]
Paralogous protein(s)
[protein|C6B0ACB9D9703DD8141FD7D9D62DB22FB48F458B|yknV], [protein|D5A3C316BD4567A0155F70330E32ACDE18F063FE|ywjA], [protein|E85814EDF232D21A42380D559EAD2CDFB41F19DB|yfiC], [protein|ED1F82463BAA28B67184BFAB5CB23CF26A62999D|bmrA], [protein|0EB4D3E1B9AF39ECCBD79EB559FAE5BB0EE4C156|ygaD], [protein|288CA73D93B1E5106E1C6CE5E7E2E8BE2A6BD3F3|yfiB], [protein|67C0C9EA17EF953554D3D57CD0D285246F50C1AD|bmrC]
[wiki|Localization]
cell membrane [Pubmed|10092453]
Expression and Regulation
Operons
genes
[gene|70D7098BEBD5E53B4B9B8C3394FAAF972C65EE22|yknU]-[gene|C6B0ACB9D9703DD8141FD7D9D62DB22FB48F458B|yknV]-[gene|916419C4ED113778488EBC558A35810498028B02|yknW]-[gene|FD270195901B89DAAAD134DB9DE729670A9BDECF|yknX]-[gene|FE3A01BEA974C5E32C68DC600C800E5EF101B34F|yknY]-[gene|9680326BAA94A503E2A5C6F0A2479AE0B0467B4C|yknZ]
description
[Pubmed|22383849]
Biological materials
Mutant
MGNA-B346 (yknU::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1345 NBRP B. subtilis, Japan]
BKE14320 ([gene|70D7098BEBD5E53B4B9B8C3394FAAF972C65EE22|yknU]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE14320 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCCAGCACCTTTCCAA, downstream forward: _UP4_GAGGTCGGATAGGGAGGGGC
BKK14320 ([gene|70D7098BEBD5E53B4B9B8C3394FAAF972C65EE22|yknU]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK14320 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCCAGCACCTTTCCAA, downstream forward: _UP4_GAGGTCGGATAGGGAGGGGC
References
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Time of last update: 2024-04-17 12:59:22
Author of last update: Melvin.boenninger