yoaB
168
2-oxoglutarate permease (proton symporter)
locus
BSU_18540
Molecular weight
45.22 kDa
pI
9.41
function
uptake of alpha-ketoglutarate
product
2-oxoglutarate permease (proton symporter)
essential
no
synonyms
yoaB
Outlinks
Genomic Context
Categories containing this gene/protein
List of homologs in different organisms, belongs to COG2814 (Galperin et al., 2021)
This gene is a member of the following regulons
Gene
Coordinates
2,021,223 → 2,022,467
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The protein
Protein family
[wiki|major facilitator superfamily] (according to UniProt)
[wiki|Sugar transporter (TC 2.A.1.1) family] (according to UniProt)
Structure
[AF|O34864]
Paralogous protein(s)
[protein|12B260DBC4E29151364251837FD227593D0BF391|csbX]
[wiki|Localization]
membrane [Pubmed|18763711]
Expression and Regulation
Operons
genes
[gene|3769B79A180412C0FE98B3FC54BA49750BAFEDF6|yoaD]-[gene|182B8EFA41DAE695B008CBAA561F3730D11750B1|yoaC]-[gene|FF60633F2902E4CA58B34FF3DAFF85B0D4007622|yoaB]
description
[Pubmed|10094622]
regulation
induced by methionine starvation ([wiki|S-box]) [Pubmed|10094622]
the [wiki|S-box] RNA is degraded by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [pubmed|29794222]
regulatory mechanism
S-box: RNA switch, , the [wiki|S-box] [wiki|riboswitch] binds S-adenosylmethionine resulting in termination [Pubmed|10094622], in [regulon|other_regulator:S-box|S-box]
Biological materials
Mutant
MGNA-A833 (yoaB::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/833 NBRP B. subtilis, Japan]
BKE18540 (Δ[gene|FF60633F2902E4CA58B34FF3DAFF85B0D4007622|yoaB]::erm trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE18540 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCTGTCTCCTCCTTAG, downstream forward: _UP4_TAATTAGAAAGCGCCCTGTT
BKK18540 (Δ[gene|FF60633F2902E4CA58B34FF3DAFF85B0D4007622|yoaB]::kan trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK18540 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCTGTCTCCTCCTTAG, downstream forward: _UP4_TAATTAGAAAGCGCCCTGTT
References
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Time of last update: 2024-04-19 19:08:27
Author of last update: Melvin.boenninger