yrkQ

yrkQ
168

two-component sensor kinase

locus
BSU_26420
Molecular weight
49.56 kDa
pI
5.16
Protein length
Gene length
function
unknown
product
two-component sensor kinase
essential
no
synonyms
yrkQ

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG2205 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
2,703,150  2,704,448
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The protein
Catalyzed reaction/ biological activity
autophosphorylation, phosphorylation of [protein|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]
ATP + protein L-histidine --> ADP + protein N-phospho-L-histidine (according to UniProt)
[wiki|Domains]
two transmembrane segments, C-terminal histidine phosphotransferase domain
[wiki|HAMP domain] (aa 167-219) (according to UniProt)
[wiki|Histidine kinase domain] (aa 234-432) (according to UniProt)
Structure
[AF|P54444]
Modification
autophosphorylation on a His residue
[wiki|Localization]
cell membrane (according to UniProt)
Expression and Regulation
Operons
genes
[gene|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]-[gene|8A38FEFAA0FF91D989B77D40CBB3741902DC9D67|yrkQ]-[gene|E0DF6DE230AD0B632EEC0A1FB11EB32E59BD573E|yrkR]
description
[Pubmed|18175906]
regulatory mechanism
[protein|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]: activation, [Pubmed|18175906], in [regulon|protein:1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP regulon]
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[gene|1582F9E6510C4FA87B3A5F3F4A7F39008C654AA9|yrkP]→[gene|E0DF6DE230AD0B632EEC0A1FB11EB32E59BD573E|yrkR]

2024-02-21 01:18:19

ghost

40

e3d063de09cd9c4d97c8ec82b566de3adad28a57

9CC2987CFD31A5505E51ACD9A4B0D933B757785A

Biological materials
Mutant
MGNA-C423 (yrkQ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/2421 NBRP B. subtilis, Japan]
BKE26420 ([gene|8A38FEFAA0FF91D989B77D40CBB3741902DC9D67|yrkQ]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE26420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_AGCCAGTTTTTTGGTTAGCG,  downstream forward: _UP4_TAGGCTGAGAATAAAAACCA
BKK26420 ([gene|8A38FEFAA0FF91D989B77D40CBB3741902DC9D67|yrkQ]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK26420 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_AGCCAGTTTTTTGGTTAGCG,  downstream forward: _UP4_TAGGCTGAGAATAAAAACCA
References
10094672,18175906

8A38FEFAA0FF91D989B77D40CBB3741902DC9D67

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Time of last update: 2024-03-27 22:15:52

Author of last update: Melvin.boenninger