ytlP

ytlP
168

similar to 2´-CPDase

locus
BSU_29960
Molecular weight
21.00 kDa
pI
8.5
Protein length
Gene length
function
nucleotide metabolism
product
putative 2´-CPDase
essential
no
synonyms
ytlP

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1514 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,065,751  3,066,302
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The protein
Catalyzed reaction/ biological activity
H2O + RNA(n)-2',3'-cyclic phosphate --> H+ + RNA(n)-2'- phosphate (according to UniProt)
Protein family
2H phosphoesterase superfamily (with [protein|5CA17CD28A725B8D7B87B9AAA167844042439794|yjcG], according to UniProt) [pubmed|31422053]
Structure
[PDB|1IUH] (from Thermus thermophilus, 24% identity) [pubmed|12798681]
[AF|O34570]
Paralogous protein(s)
[protein|5CA17CD28A725B8D7B87B9AAA167844042439794|yjcG]
Expression and Regulation
Operons
genes
[gene|29A38D244A07ED0973D0846B652238524F4DBC67|ytlP]-[gene|DB1491F13F8B55A360413E815E47A2B51D24395C|ytlQ]-[gene|ED4C1EA16FF96DA20F12B972CD2458FA3B49DDA5|ytlR]-[gene|7D783DD180D950A4B030BF5EA78CCE930A466A07|amyX]
description
[pubmed|22383849]
sigma factors
[protein|7024E4162A6D827069F882FDEACA696EBC05DD40|sigD]: sigma factor, [Pubmed|26577401], in [regulon|protein:7024E4162A6D827069F882FDEACA696EBC05DD40|sigD regulon]
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[gene|29A38D244A07ED0973D0846B652238524F4DBC67|ytlP]->[gene|7D783DD180D950A4B030BF5EA78CCE930A466A07|amyX]

2024-03-28 08:18:10

Bzhu

41

2576b9a8551e42406fc3edaa2ce292ee1e219bc5

1F3E1F8E1B45662409D2F7E8989E008A048927D9

Biological materials
Mutant
MGNA-A431 (ytlP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/431 NBRP B. subtilis, Japan]
BKE29960 ([gene|29A38D244A07ED0973D0846B652238524F4DBC67|ytlP]::erm  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKE29960 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCGTCTGACACTCCCTT,  downstream forward: _UP4_TAATTCATTGCGGAGTGGAG
BKK29960 ([gene|29A38D244A07ED0973D0846B652238524F4DBC67|ytlP]::kan  trpC2) available at [http://bgsc.org/getdetail.php?bgscid=BKK29960 BGSC],  [Pubmed|28189581], upstream reverse: _UP1_CATCCGTCTGACACTCCCTT,  downstream forward: _UP4_TAATTCATTGCGGAGTGGAG
References
17012785,12798681,31422053

29A38D244A07ED0973D0846B652238524F4DBC67

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Time of last update: 2024-03-27 00:48:04

Author of last update: Jstuelk