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spoVT
transcription activator and repressor of [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG]-dependent genes
function
regulation of forespore gene expression
product
transcriptional regulator
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]Gene
Coordinates
64,099 64,635
The protein
Paralogous protein(s)
[protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB][protein|5872812AB61E92E2944E926915EB7FEE71BFA6D5|Abh]: [SW|Domains]
[SW|SpoVT-AbrB domain] (aa 5-51) (according to UniProt)Structure
[PDB|2W1R] (full-length), [PDB|2W1T] (C-terminal domain) [PDB|2RO5] (recognition domain)[SW|Localization]
Cytoplasm (Homogeneous) [Pubmed|16479537]Expression and Regulation
Operons
genes
[gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]
description
[Pubmed|8755877]
sigma factors
[protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF]: sigma factor, [Pubmed|15699190], in [regulon|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF regulon][protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG]: sigma factor, [Pubmed|15699190,8755877], in [regulon|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG regulon]regulation
expressed in the forespore ([protein|search|SigG]) [Pubmed|8755877]view in new tabgenes
[gene|C595D32D98723E93AF26B5C864FD61AF4739E069|fin]-[gene|AD1F39823ABCE2A222259B879513752942C59590|mfd]-[gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]
description
[pubmed|22383849]
view in new tabBiological materials
Mutant
BKE00560 ([gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE00560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGGTGCCTCTCTTT, downstream forward: _UP4_TAGGTCTTATTCCTTTCTTCBKK00560 ([gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK00560 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATCTCTGGTGCCTCTCTTT, downstream forward: _UP4_TAGGTCTTATTCCTTTCTTCReferences
Reviews
Original Publications
16497325,18996130,15063493,8755877,16479537,16159768,22522895,15980461,27790204