spoVT

transcription activator and repressor of SigG-dependent genes

locus: BSU00560

pI: 4.68

mw: 19.60 kDa

protein length: 178 aa

gene length: 534 bp

function: regulation of forespore gene expression

product: transcriptional regulator

essential: no

synonyms: yabL

Genomic Context

categories

• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
• [category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other]

Gene

Coordinates: 64,099 → 64,635

The protein

Paralogous protein(s)

• [protein|E5110D9C36E8C55AFD1419987B14A53232165F20|AbrB], [protein|5872812AB61E92E2944E926915EB7FEE71BFA6D5|Abh] (only the N-terminal domains (aa 1 through 50) are conserved between SpoVT and the two paralogues)

Structure

• [PDB|2W1R] (full-length), [PDB|2W1T] (C-terminal domain) [PDB|2RO5] (recognition domain)

[SW|Localization]

• Cytoplasm (Homogeneous) [Pubmed|16479537]

Expression and Regulation

Operons

• genes: [gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]
  description: [Pubmed|8755877]

  sigma factors

  • [protein|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF]: sigma factor, [Pubmed|15699190], in [regulon|CFF318EE6CACDEE763FBF96A2ABB46E944679AAA|SigF regulon]
  • [protein|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG]: sigma factor, [Pubmed|15699190,8755877], in [regulon|5F24258282F3166B7696B9E9ABC1706E4D06C944|SigG regulon]

  regulation

  • expressed in the forespore ([protein|search|SigG]) [Pubmed|8755877]

• genes: [gene|C595D32D98723E93AF26B5C864FD61AF4739E069|fin]-[gene|AD1F39823ABCE2A222259B879513752942C59590|mfd]-[gene|01EF886D3D004EA9B22AC5E75D50FF07D8631E68|spoVT]
  description: [pubmed|22383849]

References

• 16497325,18996130,15063493,8755877,16479537,16159768,22522895,15980461,27790204