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sdpB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]
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sdpB [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

membrane protein, required for SdpC toxin maturation
locus
BSU33760
pI
9.52
mw
37.00 kDa
function
maturation of the SdpC toxin
product
unknown
essential
no
synonyms
yvaX

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.17|Toxins, antitoxins and immunity against toxins]
  • [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]
  • [SW|Categories] containing this gene/protein

  • [SW|toxins, antitoxins and immunity against toxins], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|Rok regulon], [SW|Spo0A regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,464,762 -> 3,465,733

    The protein

    [SW|Localization]

  • cell membrane [Pubmed|18763711]
  • Expression and Regulation

    Operon

  • ''[protein|search|sdpA]-[protein|search|sdpB]-[protein|search|sdpC]'' [Pubmed|12817086]
  • Regulation

  • expressed under conditions that trigger sporulation ([SW|Spo0A]) [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647,15687200 PubMed]
  • repressed by [protein|search|Rok] [Pubmed|15743949]
  • repressed during logrithmic growth ([protein|search|AbrB]) [http://www.ncbi.nlm.nih.gov/sites/entrez/15687200,17720793 PubMed]
  • strongly repressed in response to glucose starvation in M9 medium [Pubmed|23033921]
  • Regulatory mechanism

  • [SW|Spo0A]: transcription activation [http://www.ncbi.nlm.nih.gov/sites/entrez/14651647,15687200 PubMed]
  • [protein|search|Rok]: transcription repression [Pubmed|15743949]
  • [protein|search|AbrB]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/15687200,17720793 PubMed]
  • Additional information

  • the amount of the mRNA is substantially decreased upon depletion of [Rny|search|RNase Y] [PubMed|21815947]
  • References

    Reviews

  • 20955377
  • Original Publications

  • 12817086,14651647,15687200,15743949,15687200,17720793,18763711,23687264,21815947,23033921