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racA [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]
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racA [Tue Dec 13 2016 11:16:37 GMT+0100 (CET)]

cell division protein: attaches the chromosome to the cell pole at the onset of sporulation
locus
BSU37030
pI
9.00
mw
20.00 kDa
product
cell division protein
essential
no
synonyms
ywkC

Genomic Context

      

categories

  • [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.8|Cell division] → [category|SW 1.1.8.2|Other genes]
  • [SW|Categories] containing this gene/protein

  • [SW|cell division], [SW|sporulation proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|SigH regulon], [SW|Spo0A regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    3,798,789 -> 3,799,343

    The protein

    Protein family

  • racA family (according to Swiss-Prot)
  • Structure

  • [PDB|5I44] (RacA-DN complex) [Pubmed|27085804]
  • [PDB|5I41] (DNA-binding domain) [Pubmed|27085804]
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • [SW|Interactions]

  • [protein|search|RacA] is a member of a suspected group of hubs proteins that were suggested to be involved in a large number of [SW|interactions] [Pubmed|21630458]
  • [protein|search|RacA]-[protein|search|DisA] [Pubmed|12493822]
  • [protein|search|RacA]-[SW|DivIVA] [Pubmed|19478798], [protein|search|RacA] binds to the C-terminal domain of [SW|DivIVA][Pubmed|23264578], this results in anchoring the centromere to the cell pole [Pubmed|27085804]
  • Expression and Regulation

    Operon

  • ''racA'' (according to [http://dbtbs.hgc.jp/COG/prom/racA.html DBTBS])
  • [SW|Sigma factor]

  • [protein|search|SigH] [Pubmed|12493822]
  • Regulation

  • expressed under conditions that trigger sporulation ([SW|Spo0A]) [Pubmed|12493822,14651647,15687200]
  • Regulatory mechanism

  • [SW|Spo0A]: transcription activation [Pubmed|12493822,14651647,15687200]
  • References

  • 27085804,15780934,19478798,12493822,12950914,21630458,14651647,15687200,12493822,23264578