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aimA
function
uptake of serine
product
amino acid importer A
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.1|Amino acid transporters] → [category|SW 1.2.4.1.4|APC superfamily][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.1|Biosynthesis/ acquisition of amino acids] → [category|SW 2.3.1.8|Biosynthesis/ acquisition of serine/ glycine/ alanine][category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.2|Utilization of amino acids] → [category|SW 2.3.2.7|Utilization of alanine/ serine][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
231,348 232,967
Phenotypes of a mutant
resistant to serine [pubmed|32743959]The protein
Catalyzed reaction/ biological activity
uptake of serine [pubmed|32743959]Protein family
[SW|amino acid-polyamine-organocation (APC) superfamily] (according to UniProt)Paralogous protein(s)
[protein|3AC4ED647836A1633DC3439BB4F3A74FA78CF2DB|YveA] Structure
[PDB|6F2G] from Carnobacterium sp. AT7, 24.8% identity [pubmed|31000719][SW|Localization]
membrane [Pubmed|18763711]Expression and Regulation
Operons
genes
[gene|151A61315ADAA7213502F15C0C0ED636A4C3EA7C|aimA]
description
[pubmed|22383849]
view in new tabBiological materials
Mutant
GP1886 Δ[gene|151A61315ADAA7213502F15C0C0ED636A4C3EA7C|aimA]::cat, available in [SW|Jörg Stülke]'s lab [pubmed|32743959]GP2786 Δ[gene|151A61315ADAA7213502F15C0C0ED636A4C3EA7C|aimA]::aphA3, available in [SW|Jörg Stülke]'s lab [pubmed|32743959]MGNA-B963 (ybeC::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1962 NBRP B. subtilis, Japan]BKE02120 ([gene|151A61315ADAA7213502F15C0C0ED636A4C3EA7C|aimA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE02120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCGTAAACACCTTTCA, downstream forward: _UP4_TAAAATATAGAAGAAAACCTBKK02120 ([gene|151A61315ADAA7213502F15C0C0ED636A4C3EA7C|aimA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK02120 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATATCGTAAACACCTTTCA, downstream forward: _UP4_TAAAATATAGAAGAAAACCTGP2831 (''Δ''''[gene|533EEB1A454D29800C9A00A0BE107ECEE2138DAB|gltT]''::''aphA3'' ''Δ''''[gene|151A61315ADAA7213502F15C0C0ED636A4C3EA7C|aimA]''::''phleo''), available in [SW|Jörg Stülke]'s lablacZ fusion
pGP2287 (in [SW|pAC5]) (GP2965), available in [SW|Jörg Stülke]'s lab [pubmed|32743959]FLAG-tag construct
GP3062 ''ybeC-3xFLAG spc'' (based on [SW|pGP1331]), available in [SW|Jörg Stülke]'s labReferences
18763711,31000719,32743959