nhaK [Tue Dec 13 2016 11:16:36 GMT+0100 (CET)]

cation/H antiporter

locus: BSU33420

pI: 9.00

mw: 75.00 kDa

function: monovalent cation export

product: cation/H antiporter

essential: no

synonyms: yvgP

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.4|Transporters/ other] → [category|SW 1.2.4.5|Metal ion transporter]
• [category|SW 1|Cellular processes] → [category|SW 1.3|Homeostasis] → [category|SW 1.3.1|Metal ion homeostasis (K, Na, Ca, Mg)] → [category|SW 1.3.1.2|Sodium uptake/ export]
• [category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]

[SW|Categories] containing this gene/protein

• [SW|transporters/ other], [SW|metal ion homeostasis (K, Na, Ca, Mg)], [SW|membrane proteins]

Gene

Coordinates on the chromosome (coding sequence): 3,428,331 -> 3,430,343

The protein

Catalyzed reaction/ biological activity

• export of Na(), K(), Li(), Rb()

[SW|Localization]

• cell membrane (according to Swiss-Prot)

Expression and Regulation

Operon

• ''[protein|search|nhaK]'' [Pubmed|16021482]

Regulation

• constitutive, expression increases in the presence of Na() and K() [Pubmed|16021482]

Biological materials

Mutant

• MGNA-A455 (yvgP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/455 NBRP B. subtilis, Japan]
• GP2226 (''[protein|search|nhaK]''::''aphA3''), available in [SW|Jörg Stülke]'s lab

References

• 16021482