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yugJ
similar to NADH-dependent butanol dehydrogenase
Genomic Context
categories
[category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]Gene
Coordinates
3,223,471 3,224,634
The protein
Protein family
iron-containing alcohol dehydrogenase family (with [protein|B90D4E798145F2AF3421DDC5AB6CD578E2E17900|GbsB] and [protein|D81610C7CA2A92FCB1195591ACB613E7C1288F6B|YugK], according to UniProt)Paralogous protein(s)
[protein|D81610C7CA2A92FCB1195591ACB613E7C1288F6B|YugK] Structure
[PDB|1VLJ] (from Thermotoga maritima, 44% identity)Expression and Regulation
Operons
genes
[gene|1E951C2B640966643D5F081159522CD1C51942C8|yugJ]
description
[Pubmed|9274030]
regulatory mechanism
[protein|2C6386E9A63F410558D168798D077DF91590F454|Spx]: activation, [Pubmed|14597697,19575568], in [regulon|2C6386E9A63F410558D168798D077DF91590F454|Spx regulon]view in new tabBiological materials
Mutant
MGNA-B549 (yugJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1548 NBRP B. subtilis, Japan]BKE31370 ([gene|1E951C2B640966643D5F081159522CD1C51942C8|yugJ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE31370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACATCTCCTCCTTAGA, downstream forward: _UP4_TAAAAAAAGGGGAAATAGCCBKK31370 ([gene|1E951C2B640966643D5F081159522CD1C51942C8|yugJ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK31370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACATCTCCTCCTTAGA, downstream forward: _UP4_TAAAAAAAGGGGAAATAGCCReferences
Reviews
Original publications
The corresponding protein in ''E. coli