SubtiBank SubtiBank
yugJ
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yugJ

similar to NADH-dependent butanol dehydrogenase
locus
BSU_31370
pI
5.22
mw
42.57 kDa
protein length
387 aa Sequence Blast
gene length
1164 bp Sequence Blast
function
unknown
product
unknown
essential
no
synonyms
Outlinks
KEGGBsubCycSubtiListUniProtExpression Browser

Genomic Context

      

categories

  • [category|SW 6|Groups of genes] → [category|SW 6.6|Poorly characterized/ putative enzymes]

    • Gene

    Coordinates
    3,223,471 3,224,634

    The protein

    Protein family

  • iron-containing alcohol dehydrogenase family (with [protein|B90D4E798145F2AF3421DDC5AB6CD578E2E17900|GbsB] and [protein|D81610C7CA2A92FCB1195591ACB613E7C1288F6B|YugK], according to UniProt)

    • Paralogous protein(s)

  • [protein|D81610C7CA2A92FCB1195591ACB613E7C1288F6B|YugK]

    • Structure

  • [PDB|1VLJ] (from Thermotoga maritima, 44% identity)

    • Expression and Regulation

    Operons

    genes
    [gene|1E951C2B640966643D5F081159522CD1C51942C8|yugJ]
    description
    [Pubmed|9274030]

    regulatory mechanism

  • [protein|2C6386E9A63F410558D168798D077DF91590F454|Spx]: activation, [Pubmed|14597697,19575568], in [regulon|2C6386E9A63F410558D168798D077DF91590F454|Spx regulon]
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    Biological materials

    Mutant

  • MGNA-B549 (yugJ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1548 NBRP B. subtilis, Japan]
  • BKE31370 ([gene|1E951C2B640966643D5F081159522CD1C51942C8|yugJ]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE31370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACATCTCCTCCTTAGA, downstream forward: _UP4_TAAAAAAAGGGGAAATAGCC
  • BKK31370 ([gene|1E951C2B640966643D5F081159522CD1C51942C8|yugJ]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK31370 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGACATCTCCTCCTTAGA, downstream forward: _UP4_TAAAAAAAGGGGAAATAGCC

    • References

    Reviews

  • 20924577

    • Original publications

  • 9274030

    • The corresponding protein in ''E. coli

  • 20543070,18211903