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sunT [2019-09-02 13:18:17]
[protein|1A6D90298D039FFFD977B2534952BA5E32B3530F|sublancin] 168 lantibiotic [SW|ABC transporter]
function
[protein|1A6D90298D039FFFD977B2534952BA5E32B3530F|sublancin] export and processing
product
[protein|1A6D90298D039FFFD977B2534952BA5E32B3530F|sublancin] 168 lantibiotic [SW|ABC transporter]
Genomic Context
categories
[category|SW 1|Cellular processes] → [category|SW 1.2|Transporters] → [category|SW 1.2.1|ABC transporters] → [category|SW 1.2.1.2|Exporters] → [category|SW 1.2.1.2.2|Export of antibiotic substances][category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.6|Miscellaneous metabolic pathways] → [category|SW 2.6.6.1|Biosynthesis of antibacterial compounds][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.15|Biosynthesis of antibacterial compounds][category|SW 5|Prophages and mobile genetic elements] → [category|SW 5.1|Prophages] → [category|SW 5.1.2|SP-beta prophage][category|SW 6|Groups of genes] → [category|SW 6.2|Membrane proteins]Gene
Coordinates
2,267,346 2,269,463
The protein
Protein family
[SW|ABC transporter superfamily] (according to UniProt)[SW|Domains]
has both a membrane-spanning and an ATP-binding domain [Pubmed|10092453]Structure
[PDB|4RY2] (from Clostridium thermocellum, 33% identity) [pubmed|26201595][SW|Localization]
membrane [Pubmed|10092453]Biological materials
Mutant
BKE21470 (''sunT''::''erm trpC2'') available in the Bacillus Genetic Stock Center and in [SW|Jörg Stülke]'s lab [pubmed|28189581]BKE21470 ([gene|260693EE7F5B5CE2A141149D292405E84B7A5FF4|sunT]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE21470 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTTCAATCCCCGCTTTA, downstream forward: _UP4_TCGGAAAATAAGGAGTATTCBKK21470 ([gene|260693EE7F5B5CE2A141149D292405E84B7A5FF4|sunT]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK21470 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAATTTCAATCCCCGCTTTA, downstream forward: _UP4_TCGGAAAATAAGGAGTATTCReferences
Reviews
Original publications
27902860,722542,11872755,10092453,15743949,16306698,21815947,20817675,26201595