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yloI

Coenzyme A biosynthesis bifunctional protein CoaBC; putative phosphopantothenoylcysteine synthetase/decarboxylase

locus: BSU15700

pI: 6.01

mw: 43.82 kDa

protein length: 406 aa

gene length: 1218 bp

function: biosynthesis of coenzyme A

product: putative phosphopantothenoylcysteine synthetase/decarboxylase

essential: yes

ec: 4.1.1.36

synonyms: coaBC

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.4|Biosynthesis of coenzyme A]

Gene

Coordinates: 1,642,851 → 1,644,071

Phenotypes of a mutant

• essential [Pubmed|28189581]

The protein

Structure

• [PDB|1U7U] (from ''E. coli'', 41% identity in 53% fragment) [Pubmed|15530362]

Biological materials

Mutant

• MGNA-B372 (yloI::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1371 NBRP B. subtilis, Japan]

References

• 22960854,15530362,28189581