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The 21st
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ytpP
similar to thioredoxin H1
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.1|Electron transport and ATP synthesis] → [category|SW 2.1.4|Electron transport/ other/ based on similarity]Gene
Coordinates
3,054,188 3,054,511
The protein
[SW|Domains]
[SW|Thioredoxin domain] (aa 1-105) (according to UniProt)Structure
[PDB|4RUV] (Thioredoxin-2 from Staphylococcus aureus, 32% identity)Expression and Regulation
Operons
genes
[gene|314D5C01B4BDDC3B122F6D4066647B143B2A6543|ytpP]-[gene|886EF2F8A9E031FDF919E01A858C1DBC1AFF1188|ytpQ]-[gene|EE559CD606562097F09DC627F431CA31129D7BC6|ytpR]
description
[Pubmed|21949854]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|21949854], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[protein|2C6386E9A63F410558D168798D077DF91590F454|Spx]: activation, [Pubmed|21949854], in [regulon|2C6386E9A63F410558D168798D077DF91590F454|Spx regulon]view in new tabBiological materials
Mutant
MGNA-B531 (ytpP::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/1530 NBRP B. subtilis, Japan]BKE29840 ([gene|314D5C01B4BDDC3B122F6D4066647B143B2A6543|ytpP]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE29840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCATATCCCTCCAGTT, downstream forward: _UP4_AAAGCGTAAAGGAGGACATCBKK29840 ([gene|314D5C01B4BDDC3B122F6D4066647B143B2A6543|ytpP]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK29840 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATTTCATATCCCTCCAGTT, downstream forward: _UP4_AAAGCGTAAAGGAGGACATCReferences