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papA [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]
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papA [Tue Dec 13 2016 11:16:34 GMT+0100 (CET)]

Xaa-Pro amino-peptidase
locus
BSU24460
pI
4.00
mw
37.00 kDa
function
degradation of proline-containing peptides
product
Xaa-Pro amino-peptidase
essential
no
ec
3.4.11.9
synonyms
yqhT

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.3|Amino acid/ nitrogen metabolism] → [category|SW 2.3.3|Utilization of nitrogen sources other than amino acids] → [category|SW 2.3.3.4|Utilization of peptides]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.6|Coping with hyper-osmotic stress]
  • [SW|Categories] containing this gene/protein

  • [SW|utilization of nitrogen sources other than amino acids], [SW|coping with hyper-osmotic stress], [SW|sporulation/ other]
  • Gene

    Coordinates on the chromosome (coding sequence)
    2,538,697 -> 2,539,758

    Phenotypes of a mutant

  • inactivation of ''[SW|papA]'' reduces sporulation efficiency to 1.2% that of wild type cells; delayed entry into sporulation [Pubmed|26735940]
  • The protein

    Protein family

  • peptidase M24B family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|PapB]
  • Structure

  • [PDB|3Q6D] (the ''B. anthracis'' enzyme, 65% identity, 82% similarity)
  • [SW|Localization]

  • cytoplasm (according to Swiss-Prot)
  • Biological materials

    Mutant

  • available in the [SW|Erhard Bremer] lab
  • Labs working on this gene/protein

  • [SW|Erhard Bremer], Marburg University, Germany [http://www.uni-marburg.de/fb17/fachgebiete/mikrobio/molmibi Homepage]
  • References

  • 23144141,26735940