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racE

glutamate racemase

locus: BSU_28390

pI: 4.86

mw: 29.85 kDa

protein length: 272 aa

gene length: 819 bp

function: peptidoglycan precursor biosynthesis

product: glutamate racemase

essential: yes

ec: 5.1.1.3

synonyms: glr

Genomic Context

categories

• [category|SW 1|Cellular processes] → [category|SW 1.1|Cell envelope and cell division] → [category|SW 1.1.1|Cell wall synthesis] → [category|SW 1.1.1.1|Biosynthesis of peptidoglycan]
• [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.1|Biosynthesis of cell wall components] → [category|SW 2.6.1.1|Biosynthesis of peptidoglycan]
• [category|SW 6|Groups of genes] → [category|SW 6.1|Essential genes]

Gene

Coordinates: 2,903,217 2,904,035

Phenotypes of a mutant

• essential [Pubmed|12682299]

The protein

Catalyzed reaction/ biological activity

• L-glutamate --> D-glutamate (according to UniProt)

Protein family

• aspartate/glutamate racemases family (with [protein|BBEE8CEC868D3B781BEA50C45935BC810EA7A4FB|YrpC] and [protein|2ABCC493C6CA847A7BC65B1200A9B6490621462A|RacX], according to UniProt)

Paralogous protein(s)

• [protein|BBEE8CEC868D3B781BEA50C45935BC810EA7A4FB|YrpC]

Structure

• [PDB|1ZUW] (with D-glutamate)

Expression and Regulation

Operons

• genes: [gene|FBD63332ABDEA7D4837396A0617DA51153781CFE|ysmB]-[gene|36FF9F097682D8BA8D7359BFEAF71ACE8E9E90D8|racE]
  description: [Pubmed|22383849]

References

• 15347750,16271894,25777674,19309142,19227983,23929705,22383849