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glpP

transcriptional antiterminator of the glpT-glpQ and glpF-glpK-glpD operons

locus: BSU_09270

pI: 8.10

mw: 21.46 kDa

protein length: 192 aa

gene length: 579 bp

function: regulation of glycerol and glycerol-3-phosphate utilization

product: transcriptional antiterminator

essential: no

synonyms

Genomic Context

categories

• [category|SW 2|Metabolism] → [category|SW 2.2|Carbon metabolism] → [category|SW 2.2.2|Utilization of specific carbon sources] → [category|SW 2.2.2.3|Utilization of glycerol/ glycerol-3-phosphate]
• [category|SW 2|Metabolism] → [category|SW 2.4|Lipid metabolism] → [category|SW 2.4.1|Utilization of lipids] → [category|SW 2.4.1.1|Utilization of phospholipids]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other]
• [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.4|RNA binding regulators]

Gene

Coordinates: 1,001,744 1,002,322

The protein

Structure

• [PDB|3KTS] (from Listeria monocytogenes, 49% identity)

Expression and Regulation

Operons

• genes: [gene|E5F6DF14A4C01B2C90F70E37908D3697BC1B5FEF|yhxA]-[gene|38767691AE7E09F46B9E97A60BF5358C1876EDF8|glpP]
  description: [Pubmed|2127799]

  sigma factors

  • [protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|21925382], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]

  additional information

  • half-life of the mRNA: 3.7 min [PubMed|21925382]
  • half-life of the mRNA: 3.7 min [PubMed|21925382]

Biological materials

Mutant

• BKE09270 ([gene|38767691AE7E09F46B9E97A60BF5358C1876EDF8|glpP]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE09270 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTGCTCCTTTAATAATT, downstream forward: _UP4_TGACACCGCTTTCATGCACT
• BKK09270 ([gene|38767691AE7E09F46B9E97A60BF5358C1876EDF8|glpP]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK09270 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTGCTCCTTTAATAATT, downstream forward: _UP4_TGACACCGCTTTCATGCACT

labs

• [SW|Josef Deutscher], Paris-Grignon, France

References

• 8825777,11929549,8436953,9595668,9493382,1479885,1809833,182672,21925382