SubtiBank SubtiBank
ylmB [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]
You are currently viewing an outdated version of SubtiWiki. Please use the newest version!

ylmB [Tue Dec 13 2016 11:16:33 GMT+0100 (CET)]

locus
BSU15350
pI
4.98
mw
47.00 kDa
function
thiamine salvage
product
N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase
essential
no
synonyms

Genomic Context

      

categories

  • [category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.2|Biosynthesis of cofactors] → [category|SW 2.6.2.3|Biosynthesis/ acquisition of thiamine]
  • [SW|Categories] containing this gene/protein

  • [SW|biosynthesis of cofactors]
  • This gene is a member of the following [SW|regulons]

  • [SW|Thi-box]
  • Gene

    Coordinates on the chromosome (coding sequence)
    1,607,556 -> 1,608,836

    The protein

    Catalyzed reaction/ biological activity

  • N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine + H2O = formate + 4-amino-5-aminomethyl-2-methylpyrimidine (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|YodQ]
  • [SW|Cofactors]

  • Binds 2 zinc or cobalt ions per subunit (according to Swiss-Prot)
  • Expression and Regulation

    Regulation

  • repressed by thiamine ([protein|search|Thi-box]) [Pubmed|12376536]
  • Regulatory mechanism

  • [protein|search|Thi-box]: [SW|RNA switch] [Pubmed|12376536]
  • References

  • 17618314,12376536