SubtiBank SubtiBank
pspA [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]
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pspA [Tue Dec 13 2016 11:16:31 GMT+0100 (CET)]

phage shock protein A homolog
locus
BSU06180
pI
5.00
mw
24.00 kDa
function
unknown
product
unknown
essential
no
synonyms
ydjF

Genomic Context

      

categories

  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.2|Cell envelope stress proteins (controlled by SigM, V, W, X, Y)]
  • [SW|Categories] containing this gene/protein

  • [SW|cell envelope stress proteins (controlled by SigM, V, W, X, Y)], [SW|membrane proteins]
  • This gene is a member of the following [SW|regulons]

  • [SW|AbrB regulon], [SW|SigW regulon]
  • Gene

    Coordinates on the chromosome (coding sequence)
    671,245 -> 671,928

    Phenotypes of a mutant

  • more sensitive to nisin [Pubmed|23980836]
  • The protein

    Protein family

  • pspA/IM30 family (according to Swiss-Prot)
  • Paralogous protein(s)

  • [protein|search|LiaH]
  • [SW|Localization]

  • membrane protein
  • Expression and Regulation

    Operon

  • ''[protein|search|pspA]-[protein|search|ydjG]-[protein|search|ydjH]-[protein|search|ydjI]'' [Pubmed|11454200]
  • [SW|Sigma factor]

  • [protein|search|SigW] [Pubmed|11454200]
  • Regulation

  • induced by alkaline shock ([protein|search|SigW]) [Pubmed|11454200]
  • repressed during logarithmic phase ([protein|search|AbrB]) [Pubmed|18840696]
  • induced by antibiotics interacting with the cytoplasmic membrane [Pubmed|22926563]
  • induced by daptomycin [Pubmed|27791134]
  • Regulatory mechanism

  • [protein|search|AbrB]: transcription repression [Pubmed|18840696]
  • References

  • 11454200,18840696,22926563,23980836,27791134