The second international online conference
#Subtillery2021 will be held 14th - 18th June - save the date, for more information see the
conference website!
The 21st
International Conference on Bacilli has been postponed to 2022 and will take place in Prague.
alkaline phosphatase III, heptaprenylglyceryl phosphate processing phosphatase
function
aquisition of phosphate upon phosphate starvation, ether lipid synthesis
product
alkaline phosphatase III, heptaprenylglyceryl phosphate processing phosphatase
Genomic Context
categories
[category|SW 2|Metabolism] → [category|SW 2.6|Additional metabolic pathways] → [category|SW 2.6.3|Phosphate metabolism][category|SW 4|Lifestyles] → [category|SW 4.2|Sporulation] → [category|SW 4.2.1|Sporulation proteins] → [category|SW 4.2.1.4|Sporulation proteins/ other][category|SW 6|Groups of genes] → [category|SW 6.12|Secreted proteins]Gene
Coordinates
620,097 621,485
The protein
Catalyzed reaction/ biological activity
phosphate monoester + H2O --> alcohol + phosphate (according to UniProt)Protein family
alkaline phosphatase family (with [protein|E0430C16C41440633647976A0F9183E24268E198|PhoA], according to UniProt)Paralogous protein(s)
[protein|E0430C16C41440633647976A0F9183E24268E198|PhoA] Modification
phosphorylated on ser/ thr/ tyr [Pubmed|16493705]Structure
[PDB|3A52] (from ''Shewanella sp.'', 41% identity) [Pubmed|20057143][SW|Localization]
extracellular (signal peptide) [Pubmed|18957862]Expression and Regulation
Operons
genes
[gene|3B95AB3021280215B6B487A348D78FB5797AEEA6|phoB]-[gene|66D3E978E3DBA0410CA5597B5B860DF27C97335A|ydhF]
description
[Pubmed|10913081]
sigma factors
[protein|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE]: sigma factor, [Pubmed|15699190,16030210], in [regulon|3CB24D493B3282278B7DC61CE3C793DFA815F9E2|SigE regulon][protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[protein|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|PhoP]: activation, [Pubmed|9335276,10913081,16030210], in [regulon|638D6D2FCCA2A167EFED05CB4E60C2D78D5319AE|PhoP regulon]regulation
expressed under conditions of phosphate limitation ([protein|search|PhoP]) [Pubmed|9335276,10913081,16030210]view in new tabBiological materials
Mutant
1A767 ( ''phoB''::''cat''), [Pubmed|9426145], available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A767&Search=1A767 BGSC]BKE05740 ([gene|3B95AB3021280215B6B487A348D78FB5797AEEA6|phoB]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE05740 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACTGGATAACCTCCTAAA, downstream forward: _UP4_TAAAAGAATACAAGGTGTCCBKK05740 ([gene|3B95AB3021280215B6B487A348D78FB5797AEEA6|phoB]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK05740 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CAACTGGATAACCTCCTAAA, downstream forward: _UP4_TAAAAGAATACAAGGTGTCCReferences
16030210,9335276,8088554,10913081,16491025,8113174,9335276,18957862,16493705,25666134,20057143,27118079,27226549