SubtiBank SubtiBank
sigI

sigI

RNA polymerase sigma factor SigI
locus
BSU13450
pI
8.31
mw
29.04 kDa
protein length
251 aa Sequence Blast
gene length
753 bp Sequence Blast
function
control of a class of heat shock genes
product
RNA polymerase sigma factor SigI
essential
no
synonyms
ykoZ

Genomic Context

      

categories

  • [category|SW 3|Information processing] → [category|SW 3.2|RNA synthesis and degradation] → [category|SW 3.2.1|Transcription] → [category|SW 3.2.1.2|Sigma factors]
  • [category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.1|Sigma factors and their control] → [category|SW 3.4.1.1|Sigma factors]
  • [category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.4|Heat shock proteins]
  • Gene

    Coordinates
    1,411,892 → 1,412,647

    Phenotypes of a mutant

  • temperature-sensitive growth on agar plates [Pubmed|11157964]
  • The protein

    Additional information

  • overexpression of SigI suppresses ''[gene|A4C8719E06F774A6EB4D79757CC79CF89E453A54|mreB] [gene|40829C3632E9DCEB9E1C14A674B4B217F504CFE0|mreBH] [gene|6ED386D49F973C1F6B1076974F54275DD583C9D3|mbl]'' mutants [Pubmed|19114499]
  • Expression and Regulation

    Operons

    genes
    [gene|3DEAC421B4B173C6BBC700E57790751B7AFDF319|sigI]-[gene|D6C2B8ABBBD1F9F2D36C34098D5B811A15C60D3B|rsgI]
    description
    [Pubmed|17185538]

    sigma factors

  • [protein|3DEAC421B4B173C6BBC700E57790751B7AFDF319|SigI]: sigma factor, [Pubmed|17185538], in [regulon|3DEAC421B4B173C6BBC700E57790751B7AFDF319|SigI regulon]
  • regulatory mechanism

  • [protein|7F340423A34CE40D1F1AA8D373F7C4B859A6496D|WalR]: activation, [Pubmed|24125693,23199363], in [regulon|7F340423A34CE40D1F1AA8D373F7C4B859A6496D|WalR regulon]
  • regulation

  • induced at high temperature ([protein|search|SigI], [protein|search|WalR]) [Pubmed|23199363,17185538]
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    Biological materials

    Mutant

  • MGNA-A229 (ykoZ::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/229 NBRP B. subtilis, Japan]
  • References

  • 19114499,17185538,11157964,18156261,21541672,24125693,23199363,26744224