transcriptional regulator (TetR family), control of qdoI-yxaH and lmrA-lmrB
function
control of quercetin utilization
product
transcriptional regulator
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.5|Transcription factors/ other][category|SW 4|Lifestyles] → [category|SW 4.3|Coping with stress] → [category|SW 4.3.10|Resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)][SW|Categories] containing this gene/protein
[SW|transcription factors and their control], [SW|resistance against other toxic compounds (nitric oxide, phenolic acids, flavonoids, oxalate)]This gene is a member of the following [SW|regulons]
[SW|LmrA regulon], [SW|QdoR regulon]Gene
Coordinates on the chromosome (coding sequence)
4,107,352 -> 4,107,927
The protein
Protein family
[SW|TetR family]Paralogous protein(s)
[protein|search|LmrA]Effectors of protein activity
flavonoids such as quercetin act as molecular inducers and result in release from DNA targets [Pubmed|17483215,21737930]Structure
[PDB|1SGM]Expression and Regulation
Operon
''qdoR'' [Pubmed|10746760]Regulation
induced by flavonoids such as quercetin ([protein|search|QdoR], [protein|search|LmrA]) [Pubmed|17483215]Regulatory mechanism
[protein|search|LmrA]: transcription repression [Pubmed|15317768][protein|search|QdoR]: transcription repression [Pubmed|17483215]Labs working on this gene/protein
[SW|Yasutaro Fujita], University of Fukuyama, JapanReferences
Reviews
Original publications
17483215,10746760,21737930 
