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The 21st
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ywhA
similar to transcriptional regulator ([SW|MarR family])
Genomic Context
categories
[category|SW 3|Information processing] → [category|SW 3.4|Regulation of gene expression] → [category|SW 3.4.2|Transcription factors and their control] → [category|SW 3.4.2.6|Transcription factor/ other/ based on similarity]Gene
Coordinates
3,853,717 3,854,136
The protein
[SW|Domains]
[SW|HTH marR-type domain] (aa 8-139) (according to UniProt)Expression and Regulation
Operons
genes
[gene|CA74CB721842927F67FBC3B5C27D2EE46B30CE1C|thrZ]-[gene|4A3CA47533B217F595E7B600923DA31228B94DA8|ywhA]
description
[Pubmed|1379177]
sigma factors
[protein|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA]: sigma factor, [Pubmed|1379177], in [regulon|360F48D576DE950DF79C1A2677B7A35A8D8CC30C|SigA regulon]regulatory mechanism
[regulon|T-box|T-box]: anti-termination, in [regulon|T-box|T-box]regulation
induced by threonine limitation ([SW|T-box]) [Pubmed|19258532]the [SW|T-box] RNA is degraded by [protein|872CCB5A49C9000BD95E4B0472556D5F60F7D7A4|RNase Y] [pubmed|29794222]view in new tabBiological materials
Mutant
MGNA-A517 (ywhA::erm), available at the [https://shigen.nig.ac.jp/bsub/resource/strainGeneDisrupted/detail/517 NBRP B. subtilis, Japan]BKE37550 ([gene|4A3CA47533B217F595E7B600923DA31228B94DA8|ywhA]::erm trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKE37550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCAATTTCCCCATTTC, downstream forward: _UP4_TAGGGATAATAAAAGCCGGTBKK37550 ([gene|4A3CA47533B217F595E7B600923DA31228B94DA8|ywhA]::kan trpC2) available at [http://www.bgsc.org/getdetail.php?bgscid=BKK37550 BGSC], [Pubmed|28189581], upstream reverse: _UP1_CATGTCAATTTCCCCATTTC, downstream forward: _UP4_TAGGGATAATAAAAGCCGGTReferences